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. 2021 Jan 18:2021:10.17912/micropub.biology.000359.
doi: 10.17912/micropub.biology.000359.

B.2.16 is a non-lethal modifier of the Dark82 mosaic eye phenotype in Drosophila melanogaster

Alysia D Vrailas-Mortimer  1 , Nitish Aggarwal  2 , Neha N Ahmed  2 , Ian M Alberts  3 , Masa Alhawasli  2 , Ibrahim A Aljerdi  2 , Brooke M Allen  2   1 , Ahmad M Alnajar  2 , Michael A Anderson  3 , Ryan Armstong  3 , Chace C Avery  3 , Eric J Avila  3 , Tyra N Baker  3 , Soolmaz Basardeh  4 , Natasha A Bates  4 , Farrah N Beidas  3 , Ashton C Bosler  3 , Deja M Brewer  1 , Ryan S Buenaventura  4 , Natalie Jl Burrell  1 , Alyn P Cabrera-Lopez  4 , Amairani B Cervantes-Gonzalez  4 , Raymond P Cezar  4 , Joselyn Coronel  3 , Corinne Croslyn  3 , Konnor R Damery  1 , Lucero Diaz-Alavez  4 , Nupur P Dixit  2 , Dilcia L Duarte  4 , Amanda R Emke  2 , Katherine English  3 , Audrey A Eshun  1 , Samuel R Esterly  1 , Arnold J Estrada  4 , Mark Feng  4 , Meghan M Freund  1 , Niko Garcia  1 , Charandeep S Ghotra  2 , Haddia Ghyasi  4 , Christa Sa Hale  1 , Luci Hulsman  3 , Lindsey Jamerson  3 , Austin K Jones  4 , Madeline Kuczynski  1 , Takailah N Lacey-Kennedy  1 , Mindy J Lee  4 , Tala Mahjoub  2 , Molly C Mersinger  3 , Alyssa D Muckerheide  3 , David W Myers  1 , Karen Nielsen  4 , Paul J Nosowicz  2 , Jacinda A Nunez  1 , Amy C Ortiz  4 , Tulsi T Patel  2 , Natalie N Perry  3 , W Storm A Poser  3 , Deisy M Puga  4 , Cathrine Quam  3 , Paulina Quintana-Lopez  1 , Piper Rennerfeldt  3 , Nicholas M Reyes  4 , Ian G Rines  1 , Cally Roberts  3 , Daniel B Robinson  1 , Kalina M Rossa  4 , Gloria J Ruhlmann  4 , Jeremy Schmidt  3 , John R Sherwood  2 , Dimyana H Shonoda  4 , Hannah Soellner  3 , Juan C Torrez  4 , Mayukah Velide  3 , Zachary Weinzapfel  3 , Alisa C Ward  4 , Kayla L Bieser  4 , Julie A Merkle  3 , Joyce C Stamm  3 , Richard L Tillett  5 , Jacob D Kagey  2
Affiliations

B.2.16 is a non-lethal modifier of the Dark82 mosaic eye phenotype in Drosophila melanogaster

Alysia D Vrailas-Mortimer et al. MicroPubl Biol. .

Abstract

Genetic screens have been used to identify genes involved in the regulation of different biological processes. We identified growth mutants in a Flp/FRT screen using the Drosophila melanogaster eye to identify conditional regulators of cell growth and cell division. One mutant identified from this screen, B.2.16, was mapped and characterized by researchers in undergraduate genetics labs as part of the Fly-CURE. We find that B.2.16 is a non-lethal genetic modifier of the Dark82 mosaic eye phenotype.

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Figures

Figure 1. The <i>B.2.16, Dark<sup>82</sup></i> mosaic eye results in an increase in the ratio of mutant pigmented (<i>w<sup>+mC</sup></i>) tissue compared to wild type unpigmented tissue
Figure 1. The B.2.16, Dark82 mosaic eye results in an increase in the ratio of mutant pigmented (w+mC) tissue compared to wild type unpigmented tissue
A. Dark82 mosaic eye (control), mutant tissue is pigmented. B. Dark82, B.2.16 mosaic eye, mutant tissue is pigmented.
See this image and copyright information in PMC

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