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. 2021 Mar;216(3):759-768.
doi: 10.2214/AJR.20.23336. Epub 2021 Jan 21.

The Role of SPECT and PET in Epilepsy

Maria R Ponisio  1 , John M Zempel  2 , Brian K Day  2 , Lawrence N Eisenman  2 , Michelle M Miller-Thomas  1 , Matthew D Smyth  3 , R Edward Hogan  2
Affiliations

The Role of SPECT and PET in Epilepsy

Maria R Ponisio et al. AJR Am J Roentgenol. 2021 Mar.

Abstract

OBJECTIVE. The purpose of this article is to summarize the role of molecular imaging of the brain by use of SPECT, FDG PET, and non-FDG PET radiotracers in epilepsy. CONCLUSION. Quantitative image analysis with PET and SPECT has increased the diagnostic utility of these modalities in localizing epileptogenic onset zones. A multi-modal platform approach integrating the functional imaging of PET and SPECT with the morphologic information from MRI in presurgical evaluation of epilepsy can greatly improve outcomes.

Keywords: MRI; PET; SPECT; epilepsy.

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