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Review
. 2021 May;32(4):635-646.
doi: 10.1111/pai.13454. Epub 2021 Feb 27.

New concepts in pediatric rhinitis

Nikolaos G Papadopoulos  1   2 , Xenophon Aggelides  3 , Sofia Stamataki  1 , Emmanuel Prokopakis  4 , Michael Katotomichelakis  5 , Paraskevi Xepapadaki  1
Affiliations
Review

New concepts in pediatric rhinitis

Nikolaos G Papadopoulos et al. Pediatr Allergy Immunol. 2021 May.

Abstract

Rhinitis-and especially allergic rhinitis (AR)-remains the most frequent hypersensitivity condition, affecting up to a quarter of the population and impacting the quality of life of individual patients and the health economy. Data, especially with respect to underlying pathophysiologic mechanisms, mainly derive from studies on adults and are subsequently extrapolated to the pediatric population. Therapeutic algorithms for children with rhinitis are long based on the same principles as in adults. We explore and describe novel aspects of rhinitis, ranging from mechanisms to disease classification, phenotypes, diagnostic and monitoring tools, and the use of treatments, with a focus on the traits of pediatric age groups.

Keywords: allergen immunotherapy; allergic rhinitis; local allergic rhinitis; management of rhinitis; non-allergic rhinitis; pathophysiology of rhinitis.

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References

REFERENCES

    1. Samoliński B, Fronczak A, Kuna P, et al. Prevention and control of childhood asthma and allergy in the EU from the public health point of view: Polish Presidency of the European Union. Allergy. 2012;67(6):726-731.
    1. Georgountzou A, Kokkinou D, Taka S, et al. Age-dependent changes in circulating leukocytes from birth to adulthood in healthy and atopic subjects. Allergy. 2019;74(S106):139.
    1. Fokkens WJ, Lund VJ, Hopkins C, et al. European Position Paper on Rhinosinusitis and Nasal Polyps 2020. Rhinology. 2020;58(Suppl S29):1-464.
    1. Georgountzou A, Papadopoulos NG. Postnatal innate immune development: from birth to adulthood. Front Immunol. 2017;8:957.
    1. Zhong H, Fan XL, Yu QN, et al. Increased innate type 2 immune response in house dust mite-allergic patients with allergic rhinitis. Clin Immunol. 2017;183:293-299.

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