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. 2021 Jun;17(6):1026-1041.
doi: 10.1002/alz.12262. Epub 2021 Jan 21.

The economic cost of delirium: A systematic review and quality assessment

Irina Kinchin  1   2 , Eileen Mitchell  1 , Meera Agar  2 , Dominic Trépel  1
Affiliations

The economic cost of delirium: A systematic review and quality assessment

Irina Kinchin et al. Alzheimers Dement. 2021 Jun.

Abstract

Introduction: This review aims to systematically identify and appraise the methodological quality of claims on the cost of delirium; and discuss challenges and opportunities for improvements in the precision of the estimates.

Methods: Searches of scientific papers and gray literature were performed up until June 2020. The Larg and Moss checklist was used to assess the methodological quality of the included studies.

Results: After deduplication, the search identified 317 potentially relevant articles, of which 17 articles were eligible for inclusion. After adjusting for inflation and common currency, the cost of delirium ranged between $806 and $24,509 (in 2019 US$).

Discussion: This review found significant variation among the cost estimates and methodological quality. There has been limited focus on dementia as a sequela of delirium in terms of economic implications, but recent evidence suggests cost implications of delirium may be 52% higher when dementia is considered.

Keywords: cost; cost of illness; delirium; economic impact; methodology; quality assessment; systematic review.

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References

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