Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Aug;39(8):2987-2993.
doi: 10.1007/s00345-020-03567-4. Epub 2021 Jan 22.

Association between chronic kidney disease and COVID-19-related mortality in New York

Affiliations

Association between chronic kidney disease and COVID-19-related mortality in New York

Nihal E Mohamed et al. World J Urol. 2021 Aug.

Abstract

Purpose: To evaluate mortality risk of CKD patients infected with COVID-19, and assess shared characteristics associated with health disparities in CKD outcome.

Methods: We extracted the data from a case series of 7624 patients presented at Mount Sinai Health System, in New York for testing between 3/28/2020 and 4/16/2020. De-identified patient data set is being produced by the Scientific Computing department and made available to the Mount Sinai research community at the following website: https://msdw.mountsinai.org/ .

Results: Of 7624 COVID-19 patients, 7.8% (n = 597) had CKD on hospital admission, and 11.2% (n = 856) died of COVID-19 infection. CKD patients were older, more likely to have diabetes, hypertension, and chronic obstructive pulmonary disease (COPD), were current or former smokers, had a longer time to discharge, and had worse survival compared to non-CKD patients (p < 0.05). COVID-19 mortality rate was significantly higher in CKD patients (23.1% vs 10.2%) with a 1.51 greater odds of dying (95% CI: 1.19-1.90). Controlling for demographic, behavioral, and clinical covariates, the logistic regression analysis showed significant and consistent effects of CKD, older age, male gender, and hypertension with mortality (p < 0.05).

Conclusion: CKD was a significant independent predictor of COVID-19 mortality, along with older age, male gender, and hypertension. Future research will investigate the effects of COVID-19 on long-term renal function.

Keywords: COVID-19; Chronic kidney disease; Comorbidity; Mortality; Pandemic; Virus.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Results of unadjusted (a) and adjusted (b) logistic regression analyses examining the contribution of CKD, as well as demographics, behavioral factors, and comorbidities to the odds of mortality among COVID-19-positive patients. Variables were included in this analysis if they were associated with mortality at the α = 0:10 level in bivariate assessments

References

    1. World Health Organization (2020) Coronavirus Disease (COVID-19)—events as they happen World Health Organization. https://www.who.int/emergencies/diseases/novel-coronavirus-2019/events-a...
    1. ArcGIS Dashboards (2020) Coronavirus Johns Hopkins dashboard link—DEV. https://dev.to/tonetheman/coronavirus-johns-hopkins-dashboard-link-73e
    1. Duddu P, Praveen (2020) Verdict media limited. Pharmaceutical Technology. https://www.pharmaceutical-technology.com/features/covid-19-coronavirus-...
    1. WPIX (2020) Latest coronavirus updates in New York https://www.pix11.com/news/coronavirus/latest-coronavirus-updates-in-new...
    1. Reals T (2020) Coronavirus updates from April 22, 2020. CBS News, CBS Interactive https://www.cbsnews.com/live-updates/coronavirus-update-covid-19-2020-04...

LinkOut - more resources