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. 2021 Apr;12(2):313-319.
doi: 10.1007/s41999-021-00450-2. Epub 2021 Jan 24.

Contrast sensitivity is associated with frailty

Nurul Najieha Amir  1 , Shahrul Bahyah Kamaruzzaman  2 , Irina Effendi-Tenang  1 , Marium Jamaluddin  1 , Maw Pin Tan  2 , Norlina Ramli  3 , Nurliza Khaliddin  1 , Mimiwati Zahari  1
Affiliations

Contrast sensitivity is associated with frailty

Nurul Najieha Amir et al. Eur Geriatr Med. 2021 Apr.

Abstract

Purpose: Using data from the Malaysian Elders Longitudinal Research (MELoR), this study investigated the association between visual function (visual acuity and contrast sensitivity) and frailty in a group of urban-dwelling older adults.

Methods: This was a cross-sectional study. 1332 participants aged ≥ 55 years were selected by random sampling from the parliamentary electoral register. Only 1274 participants completed the frailty assessment and 1278 participants completed the contrast sensitivity assessment. Impaired vision was defined as a Snellen visual acuity of worse than 6/12 in the better eye. Poor contrast sensitivity was defined as a score on the Pelli Robson chart of lower than 1.65. Frailty was defined with the Fried's phenotype criteria. Inter-group comparisons were determined with the independent T-test for continuous variables and the Pearson's Chi-squared test for categorical variables. The odds ratio (OR) with 95% confidence interval (CI) was used to evaluate the cross-sectional association between frailty and visual function.

Results: The mean age of participants was 68.8 ± 7.5 years, of which 58.1% (774) were women. Impaired vision and poor contrast sensitivity were present in 187 (14%) and 271 (21.2%) subjects respectively. 73 (5.8%) individuals were classified as frail, 1161 (91.0.%) pre-frail, and 40 (2.8%) non-frail. There was no significant difference in frailty phenotypes between those with good and impaired vision (p = 0.241). Fried's component of handgrip strength, gait speed and exhaustion were significantly better in those with good visual function (p < 0.05). Participants with poor contrast sensitivity were significantly more likely to be frail (OR: 5.34, p = 0.004).

Conclusion: Poor contrast sensitivity was significantly associated with frailty. This highlights the importance of incorporating assessment of contrast sensitivity in those at risk of frailty.

Keywords: Aging; Frailty; MELoR; Poor contrast sensitivity; Vision impairment.

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