Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Jan;43(1):99-101.
doi: 10.1017/ice.2021.20. Epub 2021 Jan 25.

Performance of the BinaxNOW coronavirus disease 2019 (COVID-19) Antigen Card test relative to the severe acute respiratory coronavirus virus 2 (SARS-CoV-2) real-time reverse transcriptase polymerase chain reaction (rRT-PCR) assay among symptomatic and asymptomatic healthcare employees

Allison E James  1   2 , Trent Gulley  2 , Atul Kothari  2 , Kasey Holder  3 , Kelley Garner  2 , Naveen Patil  2
Affiliations

Performance of the BinaxNOW coronavirus disease 2019 (COVID-19) Antigen Card test relative to the severe acute respiratory coronavirus virus 2 (SARS-CoV-2) real-time reverse transcriptase polymerase chain reaction (rRT-PCR) assay among symptomatic and asymptomatic healthcare employees

Allison E James et al. Infect Control Hosp Epidemiol. 2022 Jan.

Abstract

The sensitivity of the BinaxNOW coronavirus disease 2019 (COVID-19) Ag Card test (BinaxNOW) was 51.6% among asymptomatic healthcare employees relative to real-time reverse transcriptase polymerase chain reaction (rRT-PCR). The odds of a positive BinaxNOW test decreased as cycle threshold value increased. BinaxNOW could facilitate rapid detection and isolation of asymptomatically infected persons in some settings while rRT-PCR results are pending.

PubMed Disclaimer

Figures

Fig 1.
Fig 1.
Distribution and median Ct values of SARS-CoV-2 rRT-PCR–positive samples from (A) symptomatic employees and (B) asymptomatic employees by BinaxNOW test result.
See this image and copyright information in PMC

References

    1. BinaxNOW COVID-19 Ag Card—Letter of Authorization, August 26, 2020. US Food & Drug Administration website. https://www.fda.gov/media/141567/download. Published 2020. Accessed January 2021.
    1. Abbott BinaxNOW COVID-19 test fact sheet. US Department of Health & Human Services (HHS) website. https://www.hhs.gov/sites/default/files/abbott-binaxnow-fact-sheet.pdf. Published 2020. Accessed January 2021.
    1. Aquino-Jarquin G. The raw Ct values from RT-PCR detection are not viral load quantitation units. Clin Infect Dis 2020;10.1093/cid/ciaa830. - DOI - PubMed
    1. Mina MJ, Parker R, Larremore DB. Rethinking COVID-19 test sensitivity—a strategy for containment. N Engl J Med 2020;10.1056/NEJMp2025631. - DOI - PubMed

MeSH terms

Substances