Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1988 Mar 15;151(2):865-71.
doi: 10.1016/s0006-291x(88)80361-9.

31P-MRS study of bio-energy recovering phenomenon

M Yoshiyama  1 , H Sakai, M Teragaki, K Takeuchi, T Takeda, M Ikata, M Ishikawa, I Miura
Affiliations

31P-MRS study of bio-energy recovering phenomenon

M Yoshiyama et al. Biochem Biophys Res Commun. .

Abstract

The ATP and creatine phosphate (PCr) contents in isolated guinea-pig hearts were determined by 31P-MRS measurement at 80.75 MHz using the Langendorff technique. Reperfusion of post-ischemic hearts with adenosine for 180 minutes increased ATP to 117.4% and decreased PCr to 59.8% of the preischemic value. Reperfusion without adenosine did not increase ATP and did not decrease PCr. The depressed cardiac function due to ischemia was remarkably improved in post-ischemic hearts by the increase in ATP due to adenosine. We found that the loss of ATP due to ischemia is not necessarily proportional to the extent of myocardial ischemic injury.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

  • Metabolomics as a tool for cardiac research.
    Griffin JL, Atherton H, Shockcor J, Atzori L. Griffin JL, et al. Nat Rev Cardiol. 2011 Sep 20;8(11):630-43. doi: 10.1038/nrcardio.2011.138. Nat Rev Cardiol. 2011. PMID: 21931361 Review.

LinkOut - more resources