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. 2020 Dec;13(12):22-26.
Epub 2020 Dec 1.

Evaluation of Intradermal Injection of Botulinum Toxin A for Facial Lifting

Enayat Mohamed Atwa  1   2   3 , Mohamed Mahmoud Nasr  1   2   3 , Howyda M Ebrahim  1   2   3
Affiliations

Evaluation of Intradermal Injection of Botulinum Toxin A for Facial Lifting

Enayat Mohamed Atwa et al. J Clin Aesthet Dermatol. 2020 Dec.

Erratum in

Abstract

BACKGROUND: Intradermal botolinum toxin A (BTXA) is an advanced technique that emerged in response to the increased demand for noninvasive facial lifting and skin rejuvenation. OBJECTIVE: We sought to evaluate the safety and efficacy of intradermal injections of BTXA for facial lifting. METHODS: Twenty-five female patients with mild symmetrical facial skin laxity were enrolled in this study. All patients were treated with BTXA in one side of the face while the other side was injected with normal saline. The response to treatment was assessed by two dermatologists who evaluated global photographs using a quartile grading scale (QGS). The patient self-assessment and satisfaction questionnaires were recorded. RESULTS: A highly significant difference was found between the side injected with BTXA and the saline injected side (control) (p<0.001). Facial lifting was achieved in 58.66 percent of the sides injected with BTXA. Forty-four percent of patients were very satisfied. Older patients showed better improvement than younger patients (p=<0.001). The results persisted for 16 weeks. No adverse effects were observed. CONCLUSION: Our results suggest that intradermal injection of BTXA could be a safe and effective therapeutic option for face lifting.

Keywords: Nonsurgical face lifting; intradermal botulinum toxin A injection; mesobotox; microbotox.

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Conflict of interest statement

FUNDING:No funding was provided for this article. DISCLOSURES:The authors report no conflicts of interest relevant to the content of this article.

Figures

FIGURE 1.
FIGURE 1.
A) Female patient, aged 50 years, with mild facial skin laxity before injection; B) The same patient after injection of left side of the face with intradermal botulinum toxin and the right side with intradermal saline, showing good improvement in facial lifting and wrinkle smoothing on the left side.
FIGURE 2.
FIGURE 2.
A) Female patient, aged 33 years, before injection; B) The same patient after injection of left side of the face with intradermal botulinum toxin and the right side with intradermal saline, showing good improvement in facial lifting on the left side with a noticeable mouth deviation.
FIGURE 3.
FIGURE 3.
A) Female patient, aged 53 years, presented with mild facial skin laxity before injection; B) The same patient after injection of left side of the face with intradermal botulinum toxin and the right side with intradermal saline, showing excellent improvement in facial lifting and wrinkle smoothing on the left side.
See this image and copyright information in PMC

References

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