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Case Reports
. 2020 Nov 11;9(1):278-281.
doi: 10.1002/ccr3.3514. eCollection 2021 Jan.

Successful treatment of adult-onset nesidioblastosis by continuous subcutaneous octreotide infusion in a patient on hemodialysis

Rina Kato  1 , Akihiro Nishimura  1 , Kimio Matsumura  1 , Shota Kikuno  1 , Kaoru Nagasawa  1 , Yasumichi Mori  1
Affiliations
Case Reports

Successful treatment of adult-onset nesidioblastosis by continuous subcutaneous octreotide infusion in a patient on hemodialysis

Rina Kato et al. Clin Case Rep. .

Abstract

Octreotide may be useful in noninsulinoma pancreatogenous hypoglycemia syndrome with nesidioblastosis patients who was on hemodialysis. Continuous octreotide subcutaneous infusion can reduce side-effects and stabilize plasma glucose levels.

Keywords: hemodialysis; nesidioblastosis; octreotide.

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Conflict of interest statement

None of the authors have any potential conflicts of interest with this report.

Figures

FIGURE 1
FIGURE 1
Results of Selective arterial calcium stimulation test. Ca, calcium stimulation; dSA, distal splenic artery; dSMA, distal superior mesenteric artery; GDA, gastroduodenal artery; PHA, proper hepatic artery; pSA, proximal splenic artery; pSMA, proximal superior mesenteric artery
FIGURE 2
FIGURE 2
Daily profile of plasma glucose (mg/dL) and insulin (µU/mL) after administration of octreotide at 50 µg/d (formula image), 75 µg/d ((formula image), and 100 µg/d ((formula image)
FIGURE 3
FIGURE 3
Clinical course of the patient. 20 d after surgery, he was still dependent on glycemic support despite the standard meals. bid, twice a day; CSI, continuous subcutaneous injection; IV, intravenous; s.c, subcutaneous injection
See this image and copyright information in PMC

References

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