Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Jan;11(1):e5-e14.
doi: 10.1055/s-0040-1721668. Epub 2021 Jan 13.

Risk of Early Birth among Women with a Urinary Tract Infection: A Retrospective Cohort Study

Rebecca J Baer  1   2   3 , Nichole Nidey  4 , Gretchen Bandoli  1 , Brittany D Chambers  3   5 , Christina D Chambers  1 , Sky Feuer  2   3 , Deborah Karasek  2   3 , Scott P Oltman  3   5 , Larry Rand  2   3 , Kelli K Ryckman  4   6 , Laura L Jelliffe-Pawlowski  3   5
Affiliations
Case Reports

Risk of Early Birth among Women with a Urinary Tract Infection: A Retrospective Cohort Study

Rebecca J Baer et al. AJP Rep. 2021 Jan.

Abstract

Objective The aim of the study is to evaluate the risk of preterm birth (PTB, <37 weeks) and early term (37 and 38 weeks) birth among women with an emergency department (ED) visit or hospitalization with a urinary tract infection (UTI) by trimester of pregnancy. Methods The primary sample was selected from births in California between 2011 and 2017. UTIs were identified from the ED or hospital discharge records. Risk of PTB, by subtype, and early term birth were evaluated by trimester of pregnancy and by type of visit using log-linear regression. Risk ratios were adjusted for maternal factors. Antibiotic usage was examined in a population of privately insured women from Iowa. Results Women with a UTI during pregnancy were at elevated risk of a birth <32 weeks, 32 to 36 weeks, and 37 to 38 weeks (adjusted risk ratios [aRRs] 1.1-1.4). Of the women with a diagnostic code for multiple bacterial species, 28.8% had a PTB. A UTI diagnosis elevated risk of PTB regardless of antibiotic treatment (aRR 1.4 for treated, aRR 1.5 for untreated). Conclusion UTIs are associated with early birth. This association is present regardless of the trimester of pregnancy, type of PTB, and antibiotic treatment.

Keywords: bacterial species; early term birth; preterm birth; trimester of infection; urinary tract infection.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest None.

Figures

Fig. 1
Fig. 1
Sample selection.
See this image and copyright information in PMC

References

    1. Delzell J E, Jr, Lefevre M L. Urinary tract infections during pregnancy. Am Fam Physician. 2000;61(03):713–721. - PubMed
    1. Lucas M J, Cunningham F G. Urinary infection in pregnancy. Clin Obstet Gynecol. 1993;36(04):855–868. - PubMed
    1. Committee on Practice Bulletins—Obstetrics, The American College of Obstetricians and Gynecologists . Practice bulletin no. 130: prediction and prevention of preterm birth. Obstet Gynecol. 2012;120(04):964–973. - PubMed
    1. National Institute for Health and Clinical Excellence Antenatal care. NICE clinical guideline 2010. Access December 09, 2019 at:https://www.nice.org.uk/guidance/qs22/documents/antenatal-care5
    1. U.S. Preventive Services Task Force . Screening for asymptomatic bacteriuria in adults: reaffirmation recommendation statement. Am Fam Physician. 2010;81(04):505. - PubMed

Publication types