Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Jan 13:10:2164956120986129.
doi: 10.1177/2164956120986129. eCollection 2021.

Precision Medicine for Breath-Focused Mind-Body Therapies for Stress and Anxiety: Are We Ready Yet?

Affiliations

Precision Medicine for Breath-Focused Mind-Body Therapies for Stress and Anxiety: Are We Ready Yet?

Helen Lavretsky et al. Glob Adv Health Med. .

Abstract

In this viewpoint, we present an argument for transdisciplinary "precision medicine" approaches that combine studies of basic neurobiology of breathing in animal and human models of stress that can help characterize physiological and neural biomarkers and mechanisms of breathing control and emotion regulation in humans. Such mechanistic research is fundamental for the development of more effective and mechanism-based mind-body therapies. The potential for this research to positively impact public health is high, as breathing techniques are inexpensive, accessible, and cross-culturally accepted, with fewer complications then observed with other standard therapies for stress-related disorders.

Keywords: anxiety; controlled paced breathing; mind-body therapies; precision medicine; stress.

PubMed Disclaimer

Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

References

    1. Acevedo BP, Pospos S, Lavretsky H. The neural mechanisms of meditative practices: novel approaches for healthy aging. Curr Behav Neurosci Rep. 2016; 3(4):328–339. - PMC - PubMed
    1. Busch V, Magerl W, Kern U, Haas J, Hajak G, Eichhammer P. The effect of deep and slow breathing on pain perception, autonomic activity, and mood processing – an experimental study. Pain Med. 2012; 13(2):215–228. - PubMed
    1. Cramer H, Lauche R, Anheyer D, et al. Yoga for anxiety: a systematic review and meta-analysis of randomized controlled trials. Depress Anxiety. 2018; 35(9):830–843. - PubMed
    1. Simon NM, Hofmann SG, Rosenfield D, et al. Efficacy of yoga vs cognitive behavioral therapy vs stress education for the treatment of generalized anxiety disorder: a randomized clinical trial. JAMA Psychiatry. 2020. doi: 10.1001/jamapsychiatry.2020.2496. - PMC - PubMed
    1. NIH, ed. The Precision Medicine Initiative Cohort Program — building a research foundation for 21st century medicine: Precision Medicine Initiative (PMI) working group report to the advisory committee to the director, NIH Bethesda, MD: National Institutes of Health; 2015. http://www.nih.gov/precisionmedicine/09172015-pmi-working-group-report.p...