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Case Reports
. 2021 Apr 1;48(4):222-231.
doi: 10.1097/OLQ.0000000000001382.

Estimates of the Prevalence and Incidence of Chlamydia and Gonorrhea Among US Men and Women, 2018

Kristen M Kreisel  1 , Emily J Weston, Sancta B St Cyr, Ian H Spicknall
Affiliations
Case Reports

Estimates of the Prevalence and Incidence of Chlamydia and Gonorrhea Among US Men and Women, 2018

Kristen M Kreisel et al. Sex Transm Dis. .

Abstract

Background: The most recent prevalence and incidence estimates for chlamydia and gonorrhea, the 2 most reported sexually transmitted infections in the United States, were for 2008. We present updated estimates of the number of prevalent and incident chlamydial and gonococcal infections for 2018.

Methods: We estimated chlamydial prevalence directly from the 2015 to 2018 cycles of the National Health and Nutrition Examination Survey and chlamydial incidence using a mathematical model primarily informed by National Health and Nutrition Examination Survey and case report data. Total and antimicrobial-resistant gonococcal prevalence and incidence were estimated using mathematical models primarily informed by case report and Gonococcal Isolate Surveillance Program data. Estimates were calculated for the total population, all women, and all men aged 15 to 39 years, stratified by age group. Primary estimates represent medians and uncertainty intervals represent the 25th (Q1) and 75th (Q3) percentiles of the empirical frequency distributions of prevalence and incidence for each infection.

Results: Among persons aged 15 to 39 years in the United States in 2018, we estimate 2.35 (Q1, 2.20; Q3, 2.51) million prevalent and 3.98 (Q1, 3.77; Q3, 4.22) million incident chlamydial infections, and an estimated 209,000 (Q1, 183,000; Q3, 241,000) prevalent and 1.57 (Q1, 1.44; Q3, 1.72) million incident gonococcal infections. Of all gonococcal infections, there were 107,000 (Q1, 94,000; Q3, 124,000) prevalent and 804,000 (Q1, 738,000; Q3, 883,000) incident infections demonstrating antimicrobial resistance or elevated minimum inhibitory concentrations to selected antibiotics.

Conclusions: Chlamydia and gonorrhea were very common in the United States in 2018. Estimates show that more than 800,000 newly acquired gonococcal infections in 2018 demonstrated resistance or elevated minimum inhibitory concentrations to currently or previously recommended antibiotics.

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Conflict of interest statement

Conflict of Interest and Sources of Funding: The authors report no conflicts of interest.

Figures

Figure 1.
Figure 1.
Ranked uncertainty impact analysis of model parameters on chlamydial incidence, by sex and age group, United States, 2018.
Figure 2.
Figure 2.
Ranked uncertainty impact analysis of model parameters on gonococcal prevalence, by sex and age group, United States, 2018.
Figure 3.
Figure 3.
Ranked uncertainty impact analysis of model parameters on gonococcal incidence, by sex and age group, United States, 2018.
See this image and copyright information in PMC

References

    1. Centers for Disease Control and Prevention. Sexually Transmitted Disease Surveillance 2018. Atlanta: U.S. Department of Health and Human Services; 2019.
    1. Stamm WE. Chlamydia trachomatis Infections of the Adult. In: Holmes KK, Sparling PF, Stamm WE, et al., eds. Sexually Transmitted Diseases. 4th ed. New York, NY: McGraw-Hill; 2008: 575–94.
    1. Hook III EW, Handsfield HH. Gonococcal Infections in the Adult. In: Holmes KK, Sparling PF, Stamm WE, et al., eds. Sexually Transmitted Diseases. 4th ed. New York, NY: McGraw-Hill; 2008: 627–45.
    1. Farley TA, Cohen DA, Elkins W. Asymptomatic sexually transmitted diseases: the case for screening. Prev Med 2003; 36(4): 502–509. - PubMed
    1. Cates W Jr, American Social Health Association Panel. Estimates of the incidence and prevalence of sexually transmitted diseases in the United States. Sex Transm Dis 1999; 26(Suppl 4): S2–S7. - PubMed

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