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Observational Study
. 2021 Mar;166(3):929-933.
doi: 10.1007/s00705-020-04914-x. Epub 2021 Jan 25.

Circulation of human coronaviruses OC43 and 229E in Córdoba, Argentina

María Emilia Ottogalli  1 , Pamela Elizabeth Rodríguez  1 , María Celia Frutos  1 , Laura Beatriz Moreno  2 , Lucía María Ghietto  1 , Cecilia Gabriela Cuffini  1 , Jorge Augusto Cámara  1 , María Pilar Adamo  1 , Laura Elena Valinotto  3 , Alicia Cámara  4
Affiliations
Observational Study

Circulation of human coronaviruses OC43 and 229E in Córdoba, Argentina

María Emilia Ottogalli et al. Arch Virol. 2021 Mar.

Abstract

This is the first study of respiratory infections in Córdoba, Argentina, caused by endemic human coronavirus (HCoV)-OC43 and HCOV-229E, which circulated during 2011-2012 at a 3% rate, either as single or multiple infections. They were detected mainly in children, but HCoV-229E was also found in adults. HCoV-229E was detected in five out of 631 samples (0.8%), and HCoV-OC43 was found in 14 out of 631 (2.2%) samples. Clinical manifestations ranged from fever to respiratory distress, and a significant association of HCoV-229E with asthma was observed. Further studies and surveillance are needed to provide better clinical insights, early diagnosis, and medical care of patients, as well as to contribute to epidemiology modeling and prevention.

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Conflict of interest statement

The authors declare that there are no competing interests.

Figures

Fig. 1
Fig. 1
Distribution of clinical specimens tested (A), cases of HCoV 229E and OC43 detected (B), and average high and low temperatures in Córdoba, Argentina, during 2011 and 2012
See this image and copyright information in PMC

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