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Case Reports
. 2021 Jun 1;46(6):485-487.
doi: 10.1097/RLU.0000000000003511.

Hemangioblastoma: An Unsuspected Pitfall in PSMA PET/CT

Nicolas Gohimont  1 , Patrice Jissendi Tchofo  2 , Marie-Lucie Racu  3 , Kim Entezari  4 , Isabelle Salmon  3 , Marianne Tondeur  1 , Diana Ene  1
Affiliations
Case Reports

Hemangioblastoma: An Unsuspected Pitfall in PSMA PET/CT

Nicolas Gohimont et al. Clin Nucl Med. .

Abstract

Hemangioblastoma (HB) is the most common primary intra-axial posterior fossa tumor in adults and is a benign vascular neoplasm. We report the case of a 73-year-old man suffering from biochemical recurrence of prostate cancer where intense overexpression of prostate-specific membrane antigen (PSMA) was observed in HB in a PSMA PET/CT. Overexpression of PSMA in tumor-associated vascular structures has been proposed as an explanation of PSMA ligand uptake in several nonprostatic tumors. Given the pathological nature of HB, this mechanism may explain the intense overexpression of PSMA observed in present case.

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Conflict of interest statement

Conflicts of interest and sources of funding: none declared.

References

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