Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1988 Jan;52(1):83-8.

Porcine focal symmetrical poliomyelomalacia: experimental reproduction with oral doses of encapsulated sodium selenite

T M Wilson  1 , R H Hammerstedt, I S Palmer, A deLahunta
Affiliations

Porcine focal symmetrical poliomyelomalacia: experimental reproduction with oral doses of encapsulated sodium selenite

T M Wilson et al. Can J Vet Res. 1988 Jan.

Abstract

Sodium selenite (encapsulated as doses of 1.4 mg, 2.6 mg and 4.2 mg per kilogram of body weight) was given orally on a daily basis to male weaner pigs, and features of these animals were compared to a control group. Porcine focal symmetrical poliomyelomalacia was produced in all experimental groups between 3 and 20 days after initiation of the treatment. Analysis of blood and several tissues revealed an elevated selenium content for all pigs. Histological lesions in the brain and the cervical lumbar/sacral spinal cord enlargements included endothelial proliferation, neuronal degeneration, microcavitation and glial cell reaction.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Vet Pathol. 1980 Nov;17(6):748-58 - PubMed
    1. Vet Pathol. 1983 May;20(3):265-73 - PubMed
    1. Vet Pathol. 1986 Jul;23(4):506-9 - PubMed
    1. Vet Rec. 1985 Jan 26;116(4):94-7 - PubMed
    1. Aust Vet J. 1985 Jun;62(6):207-9 - PubMed

Publication types

LinkOut - more resources