Risk Factors of Intervertebral Disc Pathology-A Point of View Formerly and Today-A Review
- PMID: 33494410
- PMCID: PMC7865549
- DOI: 10.3390/jcm10030409
Risk Factors of Intervertebral Disc Pathology-A Point of View Formerly and Today-A Review
Abstract
Intervertebral disc pathology is a common disorder that can be caused by genetic, mechanical, and behavioral factors; however, it is possible to slow its progression. Although environmental and behavioral factors were previously considered to be the sole causes of intervertebral disc pathologies such as disc herniation, recent studies have shown that genetic factors also play an important role. This review compares the perception of major risk factors from the last and present centuries. It also examines individual genetic and non-genetic factors acting as risk factors, as well as some approaches for preventing intervertebral disc pathologies, and compares available statistics regarding disc herniation.
Keywords: cervical; disc herniation; factors; lumbar; prevention; review; statistics; thoracic.
Conflict of interest statement
The authors declare that they have no competing interests.
Similar articles
-
Systematic Review of Outcomes Following 10-Year Mark of Spine Patient Outcomes Research Trial for Intervertebral Disc Herniation.Spine (Phila Pa 1976). 2020 Jun 15;45(12):825-831. doi: 10.1097/BRS.0000000000003400. Spine (Phila Pa 1976). 2020. PMID: 32004232
-
3D shape analyses of extant primate and fossil hominin vertebrae support the ancestral shape hypothesis for intervertebral disc herniation.BMC Evol Biol. 2019 Dec 16;19(1):226. doi: 10.1186/s12862-019-1550-9. BMC Evol Biol. 2019. PMID: 31842740 Free PMC article.
-
An Update of the Systematic Appraisal of the Accuracy and Utility of Discography in Chronic Spinal Pain.Pain Physician. 2018 Mar;21(2):91-110. Pain Physician. 2018. PMID: 29565943
-
Percutaneous treatment of cervical and lumbar herniated disc.Eur J Radiol. 2015 May;84(5):771-6. doi: 10.1016/j.ejrad.2014.02.023. Epub 2014 Mar 3. Eur J Radiol. 2015. PMID: 24673977
-
[Significance of cell autophagy in resorption of lumbar disc herniation].Zhongguo Gu Shang. 2018 Apr 25;31(4):386-390. doi: 10.3969/j.issn.1003-0034.2018.04.017. Zhongguo Gu Shang. 2018. PMID: 29772868 Review. Chinese.
Cited by
-
Ultrasound-Guided Cervical Selective Nerve Root Block versus Fluoroscopy-Guided Interlaminar Epidural Injection for Cervical Radicular Pain: A Randomized, Prospective, Controlled Study.J Pers Med. 2024 Jul 4;14(7):721. doi: 10.3390/jpm14070721. J Pers Med. 2024. PMID: 39063975 Free PMC article.
-
Epidemiology of Modic changes in dogs: Prevalence, possible risk factors, and association with spinal phenotypes.JOR Spine. 2023 Jul 21;6(3):e1273. doi: 10.1002/jsp2.1273. eCollection 2023 Sep. JOR Spine. 2023. PMID: 37780831 Free PMC article.
-
The Role of Polymorphisms in Collagen-Encoding Genes in Intervertebral Disc Degeneration.Biomolecules. 2021 Aug 26;11(9):1279. doi: 10.3390/biom11091279. Biomolecules. 2021. PMID: 34572492 Free PMC article. Review.
-
Plain Radiography: A Unique Component of Spinal Assessment and Predictive Health.Healthcare (Basel). 2024 Mar 12;12(6):633. doi: 10.3390/healthcare12060633. Healthcare (Basel). 2024. PMID: 38540597 Free PMC article. Review.
-
The causality between smoking and intervertebral disc degeneration mediated by IL-1β secreted by macrophage: A Mendelian randomization study.Heliyon. 2024 Aug 28;10(17):e37044. doi: 10.1016/j.heliyon.2024.e37044. eCollection 2024 Sep 15. Heliyon. 2024. PMID: 39286222 Free PMC article.
References
-
- De Cicco F.L., Camino Willhuber G.O. Nucleus Pulposus Herniation. [(accessed on 10 August 2020)]; Available online: https://www.ncbi.nlm.nih.gov/books/NBK542307/
-
- Ikuno A., Akeda K., Takebayashi S.-I., Shimaoka M., Okumura K., Sudo A. Genome-wide analysis of DNA methylation profile identifies differentially methylated loci associated with human intervertebral disc degeneration. PLoS ONE. 2019;14:e0222188. doi: 10.1371/journal.pone.0222188. - DOI - PMC - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources