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Comment
. 2021 Mar;18(3):188-189.
doi: 10.1038/s41571-021-00472-6.

Reply to 'Intraoperative radiotherapy for breast cancer: powerful evidence to change practice'

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Reply to 'Intraoperative radiotherapy for breast cancer: powerful evidence to change practice'

Peter D Sasieni et al. Nat Rev Clin Oncol. 2021 Mar.
No abstract available

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References

    1. Vaidya, J. S. et al. Intraoperative radiotherapy for breast cancer: powerful evidence to change practice. Nat. Rev. Clin. Oncol. https://doi.org/10.1038/s41571-021-00471-7 (2020).
    1. Sasieni, P. D. & Sawyer, E. J. Intraoperative radiotherapy for early breast cancer — insufficient evidence to change practice. Nat. Rev. Clin. Oncol. 17, 723–724 (2020). - DOI
    1. FDA. Non-Inferiority Clinical Trials to Establish Effectiveness, Guidance for Industry. https://www.fda.gov/media/78504/download (2016).
    1. Kunkler, I. H. et al. Breast-conserving surgery with or without irradiation in women aged 65 years or older with early breast cancer (PRIME II): a randomised controlled trial. Lancet Oncol. 16, 266–273 (2015). - DOI
    1. Early Breast Cancer Trialists’ Collaborative Group (EBCTCG). et al. Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials. Lancet 378, 1707–1716 (2011). - DOI

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