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. 2021 Feb;27(2):658-660.
doi: 10.3201/eid2702.203770.

Puumala Virus Infection in Family, Switzerland

Pauline Vetter, Arnaud G L'Huillier, Maria F Montalbano, Fiona Pigny, Isabella Eckerle, Giulia Torriani, Sylvia Rothenberger, Florian Laubscher, Samuel Cordey, Laurent Kaiser, Manuel Schibler

Puumala Virus Infection in Family, Switzerland

Pauline Vetter et al. Emerg Infect Dis. 2021 Feb.

Abstract

We report 3 cases of Puumala virus infection in a family in Switzerland in January 2019. Clinical manifestations of the infection ranged from mild influenza-like illness to fatal disease. This cluster illustrates the wide range of clinical manifestations of Old World hantavirus infections and the challenge of diagnosing travel-related hemorrhagic fevers.

Keywords: Hantavirus pulmonary syndrome; Puumala virus; Russia; Switzerland; hantaviruses; multiple organ failure; neutralization test; viral zoonoses; viruses; zoonoses.

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Figures

Figure
Figure
Phylogenetic tree of Puumala virus using S segment nucleotide sequences. Bold text indicates sequences isolated from family in Switzerland. GenBank accession numbers are provided in brackets. Lineages are indicated at right. Scale bar indicates number of substitutions per site.
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