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. 2021 Feb 18;384(7):671-673.
doi: 10.1056/NEJMc2027040. Epub 2021 Jan 27.

Duration of Culturable SARS-CoV-2 in Hospitalized Patients with Covid-19

Min-Chul Kim  1 , Chunguang Cui  2 , Kyeong-Ryeol Shin  2 , Joon-Yong Bae  2 , Oh-Joo Kweon  1 , Mi-Kyung Lee  1 , Seong-Ho Choi  1 , Sun-Young Jung  3 , Man-Seong Park  4 , Jin-Won Chung  5
Affiliations

Duration of Culturable SARS-CoV-2 in Hospitalized Patients with Covid-19

Min-Chul Kim et al. N Engl J Med. .
No abstract available

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Figures

Figure 1
Figure 1. Timing of Presence or Absence of Viable SARS-CoV-2 on Viral Culture and Cycle-Threshold Values for 165 Serial Samples Obtained from 21 Consecutive Patients Hospitalized with Covid-19.
Viral loads were determined with the cycle-threshold value for the N gene of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Sampling intervals ranged from 1 to 5 days (median, 2). Each circle represents a sample obtained on the specified day. Viral culture was positive only in samples with a cycle-threshold value of 28.4 or less and in those that were obtained as long as 12 days after symptom onset. Covid-19 denotes coronavirus disease 2019.
See this image and copyright information in PMC

Comment in

  • Viable SARS-CoV-2 Shedding.
    Romano CM, Felix AC, Pannuti CS. Romano CM, et al. N Engl J Med. 2021 Apr 29;384(17):1677. doi: 10.1056/NEJMc2102494. Epub 2021 Apr 6. N Engl J Med. 2021. PMID: 33822492 No abstract available.

References

    1. Allplex 2019-nCoV assay: instructions for use. Seoul, South Korea: Seegene, 2020. (Cat. no. RP10250X/RP10252W.)
    1. Response guidelines to prevent the spread of COVID-19. 8-1 Ed. Korea Disease Control and Prevention Agency, May 20, 2020. (In Korean) (http://ncov.mohw.go.kr).
    1. Hong KH, Lee SW, Kim TS, et al. Guidelines for laboratory diagnosis of coronavirus disease 2019 (COVID-19) in Korea. Ann Lab Med 2020;40:351-360. - PMC - PubMed
    1. He X, Lau EHY, Wu P, et al. Temporal dynamics in viral shedding and transmissibility of COVID-19. Nat Med 2020;26:672-675. - PubMed
    1. Reich NG, Lessler J, Cummings DAT, Brookmeyer R. Estimating incubation period distributions with coarse data. Stat Med 2009;28:2769-2784. - PubMed