Metabolic Syndrome in Obese Children-Clinical Prevalence and Risk Factors
- PMID: 33504076
- PMCID: PMC7908375
- DOI: 10.3390/ijerph18031060
Metabolic Syndrome in Obese Children-Clinical Prevalence and Risk Factors
Abstract
The prevalence of childhood obesity is increasing worldwide. Some obese children can go on to develop metabolic syndrome (MetS), but exactly who among them remains to be determined. The aim of this study was to indicate predisposing factors for metabolic syndrome, especially those that can be modified. The study comprised 591 obese children aged 10-12 years. They were all Caucasian residents of Gdańsk, Poland, with similar demographic backgrounds. Clinical examination, anthropometry, biometric impedance analysis, blood tests (including oral glucose tolerance tests (OGTT) and insulinemia), and dietary and physical activity evaluation were conducted. The results of our study show that the risk factors for MetS or any of its components include male sex, parental (especially paternal) obesity, low body mass at birth, as well as omitting breakfast or dinner. There are few risk factors for metabolic syndrome both in obese adults and children. Some of these predictors can be modified, especially those in relation to lifestyle. Identifying and then influencing these factors may help to reduce the development of metabolic syndrome and consequently improve health and quality of life.
Keywords: metabolic syndrome; obesity children; risk factors.
Conflict of interest statement
The authors declare no conflicts of interest.
Figures
Similar articles
-
Prevalence of metabolic syndrome and its associated factors in overweight and obese adolescents.J Pediatr Endocrinol Metab. 2020 Feb 25;33(2):233-239. doi: 10.1515/jpem-2019-0369. J Pediatr Endocrinol Metab. 2020. PMID: 31804963
-
Metabolic consequences of childhood obesity--a preliminary report.Ceylon Med J. 2006 Sep;51(3):105-9. doi: 10.4038/cmj.v51i3.1253. Ceylon Med J. 2006. PMID: 17315588
-
Offspring body size and metabolic profile - effects of lifestyle intervention in obese pregnant women.Dan Med J. 2014 Jul;61(7):B4893. Dan Med J. 2014. PMID: 25123127 Review.
-
Relation between circulating oxidized-LDL and metabolic syndrome in children with obesity: the role of hypertriglyceridemic waist phenotype.J Pediatr Endocrinol Metab. 2017 Nov 27;30(12):1257-1263. doi: 10.1515/jpem-2017-0239. J Pediatr Endocrinol Metab. 2017. PMID: 29127769
-
Eating Alone is Differentially Associated with the Risk of Metabolic Syndrome in Korean Men and Women.Int J Environ Res Public Health. 2018 May 18;15(5):1020. doi: 10.3390/ijerph15051020. Int J Environ Res Public Health. 2018. PMID: 29783657 Free PMC article.
Cited by
-
Prevalence and Determinants of Obesity and Overweight Among Children and Adolescents in the Middle East and North African Countries: An Updated Systematic Review.Diabetes Metab Syndr Obes. 2024 May 21;17:2095-2103. doi: 10.2147/DMSO.S458003. eCollection 2024. Diabetes Metab Syndr Obes. 2024. PMID: 38799280 Free PMC article. Review.
-
Triglyceride glucose index, pediatric NAFLD fibrosis index, and triglyceride-to-high-density lipoprotein cholesterol ratio are the most predictive markers of the metabolically unhealthy phenotype in overweight/obese adolescent boys.Front Endocrinol (Lausanne). 2023 May 10;14:1124019. doi: 10.3389/fendo.2023.1124019. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37234798 Free PMC article.
-
Metabolic Syndrome: An Updated Review on Diagnosis and Treatment for Primary Care Clinicians.J Prim Care Community Health. 2024 Jan-Dec;15:21501319241309168. doi: 10.1177/21501319241309168. J Prim Care Community Health. 2024. PMID: 39714021 Free PMC article. Review.
-
The Role of Paraclinical Investigations in Detecting Inflammation in Children and Adolescents with Obesity and Metabolic Syndrome.Life (Basel). 2024 Sep 23;14(9):1206. doi: 10.3390/life14091206. Life (Basel). 2024. PMID: 39337988 Free PMC article.
-
Unraveling Metabolic Syndrome in Youth: The Obesity Epidemic's Hidden Complication.Children (Basel). 2025 Apr 8;12(4):482. doi: 10.3390/children12040482. Children (Basel). 2025. PMID: 40310144 Free PMC article. Review.
References
-
- Obesity and Overweight. [(accessed on 30 March 2020)]; Available online: https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight.
-
- Bentham J., Di Cesare M., Bilano V., Bixby H., Zhou B., Stevens G.A., Riley L.M., Taddei C., Hajifathalian K., Lu Y., et al. Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: A pooled analysis of 2416 population-based measurement studies in 128.9 million children, adolescents, and adults. Lancet. 2017;390:2627–2642. - PMC - PubMed
-
- Silventoinen K., Jelenkovic A., Sund R., Hur Y.M., Yokoyama Y., Honda C., Hjelmborg J.B., Moller S., Ooki S., Aaltonen S., et al. Genetic and environmental effects on body mass index from infancy to the onset of adulthood: An individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) study. Am. J. Clin. Nutr. 2016;104:371–379. - PMC - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical