Rivaroxaban: Expanded Role in Cardiovascular Disease Management-A Literature Review
- PMID: 33505518
- PMCID: PMC7810545
- DOI: 10.1155/2021/8886210
Rivaroxaban: Expanded Role in Cardiovascular Disease Management-A Literature Review
Abstract
Direct oral anticoagulants (DOACs) are widely used for the prevention of stroke in nonvalvular atrial fibrillation, treatment of deep venous thrombosis and pulmonary embolism, and as prophylaxis after hip and knee surgery after approval by the Food and Drug Administration. In the last decade, DOACs were studied for various indications; this review is focused on rivaroxaban, a factor Xa inhibitor, which is used in an expanded evidence-based fashion for coronary artery disease, peripheral artery disease, heart failure, malignancy, and prophylaxis of deep venous thrombosis in acute medical illnesses.
Copyright © 2021 Muhammad Ajmal et al.
Conflict of interest statement
The authors declare that they have no conflicts of interest.
Similar articles
-
Clinical Risk Factors of Thromboembolic and Major Bleeding Events for Patients with Atrial Fibrillation Treated with Rivaroxaban in Japan.J Stroke Cerebrovasc Dis. 2020 Apr;29(4):104584. doi: 10.1016/j.jstrokecerebrovasdis.2019.104584. Epub 2020 Jan 23. J Stroke Cerebrovasc Dis. 2020. PMID: 31983518
-
Design and Rationale of the RELAXED (Recurrent Embolism Lessened by rivaroxaban, an Anti-Xa agent, of Early Dosing for acute ischemic stroke and transient ischemic attack with atrial fibrillation) Study.J Stroke Cerebrovasc Dis. 2016 Jun;25(6):1342-8. doi: 10.1016/j.jstrokecerebrovasdis.2016.01.035. Epub 2016 Mar 14. J Stroke Cerebrovasc Dis. 2016. PMID: 26987488
-
The role of rivaroxaban in atrial fibrillation and acute coronary syndromes.J Cardiovasc Pharmacol Ther. 2014 Nov;19(6):526-32. doi: 10.1177/1074248414525505. Epub 2014 Mar 21. J Cardiovasc Pharmacol Ther. 2014. PMID: 24659084 Review.
-
Cause of Death and Predictors of All-Cause Mortality in Anticoagulated Patients With Nonvalvular Atrial Fibrillation: Data From ROCKET AF.J Am Heart Assoc. 2016 Mar 8;5(3):e002197. doi: 10.1161/JAHA.115.002197. J Am Heart Assoc. 2016. PMID: 26955859 Free PMC article. Clinical Trial.
-
Direct comparative effectiveness and safety between non-vitamin K antagonist oral anticoagulants for stroke prevention in nonvalvular atrial fibrillation: a systematic review and meta-analysis of observational studies.Eur J Epidemiol. 2019 Feb;34(2):173-190. doi: 10.1007/s10654-018-0415-7. Epub 2018 Jun 8. Eur J Epidemiol. 2019. PMID: 29948370
Cited by
-
XGBoost-based machine learning test improves the accuracy of hemorrhage prediction among geriatric patients with long-term administration of rivaroxaban.BMC Geriatr. 2023 Jul 10;23(1):418. doi: 10.1186/s12877-023-04049-z. BMC Geriatr. 2023. PMID: 37430193 Free PMC article.
-
Risk Factors for Rivaroxaban-Related Bleeding Events-Possible Role of Pharmacogenetics: Case Series.Pharmacy (Basel). 2023 Feb 5;11(1):29. doi: 10.3390/pharmacy11010029. Pharmacy (Basel). 2023. PMID: 36827667 Free PMC article.
-
Evaluation of Herb-Drug Interaction Between Danshen and Rivaroxaban in Rat and Human Liver Microsomes.Front Pharmacol. 2022 Jul 19;13:950525. doi: 10.3389/fphar.2022.950525. eCollection 2022. Front Pharmacol. 2022. PMID: 35928264 Free PMC article.
-
The Antithrombotic Effect of Recombinant Neorudin on Thrombi.Drug Des Devel Ther. 2022 Jun 2;16:1667-1678. doi: 10.2147/DDDT.S353088. eCollection 2022. Drug Des Devel Ther. 2022. PMID: 35677424 Free PMC article.
-
Beyond Anticoagulation: A Comprehensive Review of Non-Vitamin K Oral Anticoagulants (NOACs) in Inflammation and Protease-Activated Receptor Signaling.Int J Mol Sci. 2024 Aug 10;25(16):8727. doi: 10.3390/ijms25168727. Int J Mol Sci. 2024. PMID: 39201414 Free PMC article. Review.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources