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Review
. 2021 Jan 15:8:2333794X20981548.
doi: 10.1177/2333794X20981548. eCollection 2021.

Tuberculosis in Pediatric Solid Organ and Hematopoietic Stem Cell Recipients

Melanie Dubois  1   2 , Avika Dixit  1   2 , Gabriella Lamb  1   2
Affiliations
Review

Tuberculosis in Pediatric Solid Organ and Hematopoietic Stem Cell Recipients

Melanie Dubois et al. Glob Pediatr Health. .

Erratum in

Abstract

Children undergoing solid organ and hematopoietic stem cell transplantation are at high risk of morbidity and mortality from tuberculosis (TB) disease in the post-transplant period. Treatment of TB infection and disease in the post-transplant setting is complicated by immunosuppression and drug interactions. There are limited data that address the unique challenges for the management of TB in the pediatric transplant population. This review presents the current understanding of the epidemiology, clinical presentation, diagnosis, management, and prevention for pediatric transplant recipients with TB infection and disease. Further studies are needed to improve diagnosis of TB and optimize treatment outcomes for these patients.

Keywords: hematopoietic stem cell transplant; pediatric tuberculosis; solid organ transplant.

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Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Pre-transplant evaluation for TB for pediatric solid organ and hematopoietic stem-cell transplant candidates and living donors. (World Health Organization 2019)(American Academy of Pediatrics)(Subramanian and Theodoropoulos, 2019)(Tomblyn, Chiller and Einsele, 2009)
See this image and copyright information in PMC

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