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. 2021 Feb 23;28(2):taab009.
doi: 10.1093/jtm/taab009.

Isolation and characterization of the new SARS-CoV-2 variant in travellers from the United Kingdom to India: VUI-202012/01 of the B.1.1.7 lineage

Pragya D Yadav  1 , Dimpal A Nyayanit  1 , Rima R Sahay  1 , Prasad Sarkale  1 , Jayshri Pethani  2 , Savita Patil  1 , Shreekant Baradkar  1 , Varsha Potdar  3 , Deepak Y Patil  1
Affiliations

Isolation and characterization of the new SARS-CoV-2 variant in travellers from the United Kingdom to India: VUI-202012/01 of the B.1.1.7 lineage

Pragya D Yadav et al. J Travel Med. .

Abstract

We have isolated the new severe acute respiratory syndrome coronavirus-2 variant of concern 202 012/01 from the positive coronavirus disease 2019 cases that travelled from the UK to India in the month of December 2020. This emphasizes the need for the strengthened surveillance system to limit the local transmission of this new variant.

Keywords: B.1.1.7 lineage; COVID-19; COVID-19 vaccines; Kent variant; South Africa; pandemic; virus variant.

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Figures

Figure 1
Figure 1
Isolation and characterization of (VOC) 202 012/01: (A) The log10 viral RNA copy number per ml of the E and RDRP genes for two different passages. Different colours are used to indicate individual isolate. (B) The cytopathic effect observed in the Vero CCL81 cell culture at passage-1 PID-4 compared to the cell control. (C) The aligned SARS-CoV-2 sequences from the UK variant isolate were compared with the reference isolate of Wuhan-HU-1 (Accession No.: NC_045512.2). The mismatches in the nucleotide position were generated using the highlighter plot (https://www.hiv.lanl.gov/cgi-bin/HIGHLIGHT/highlighter.cgi). The alignment positions are in kbps. The changes are marked in different colours.
See this image and copyright information in PMC

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