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. 2021 Jan 28;21(1):61.
doi: 10.1186/s12888-021-03051-2.

Gender difference in quality of life (QoL) among outpatients with schizophrenia in a tertiary care setting

Saleha Shafie #  1 , Ellaisha Samari #  2 , Anitha Jeyagurunathan  2 , Edimansyah Abdin  2 , Sherilyn Chang  2 , Siow Ann Chong  2 , Mythily Subramaniam  2
Affiliations

Gender difference in quality of life (QoL) among outpatients with schizophrenia in a tertiary care setting

Saleha Shafie et al. BMC Psychiatry. .

Abstract

Background: Patients with mental illness report lower quality of life (QoL) compared to the general population. Prior research has found several differences in clinical features and experiences of male and female patients with schizophrenia. Given these differences, it is also important to explore if there are any gender differences in terms of their QoL. This study aimed to investigate differences in QoL between and within each gender among outpatients with schizophrenia in Singapore.

Methods: A total of 140 outpatients were recruited through convenience sampling at the Institute of Mental Health, Singapore. QoL was measured using the brief version of World Health Organization Quality of Life (WHOQOL-BREF) which consists of four domains: physical health, psychological health, social relationships, and environment. QoL scores of males and females were compared using independent t-tests, and multiple linear regressions were used to examine sociodemographic correlates of QoL in the overall sample and within each gender.

Results: There was no significant difference in QoL domain scores between genders. Among males, Indian ethnicity (versus Chinese ethnicity) was positively associated with physical health (β=3.03, p=0.018) while males having Technical Education/ Diploma/ A level education (versus Degree and above) were positively associated with social relationships domain (β=2.46, p=0.047). Among females, Malay ethnicity (versus Chinese ethnicity) was positively associated with physical health (β=1.95, p=0.026) psychological health (β=3.21, p=0.001) social relationships (β=2.17, p=0.048) and environment (β=2.69, p=0.006) domains, while females who were separated/divorced (versus single) were inversely associated with psychological health (β=- 2.80, p=0.044) and social relationships domains (β=- 4.33, p=0.011). Females who had Secondary and below education (versus Degree and above) were inversely associated with social relationships (β=- 2.29, p=0.028) and environment domains (β=- 1.79, p=0.048).

Conclusions: The findings show the importance of treatments targeting QoL to attend to both the clinical features of the illness as well patient's sociodemographic characteristics.

Keywords: Gender differences; Quality of life; Schizophrenia.

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Conflict of interest statement

The authors declare that they have no competing interests.

References

    1. Murray CJL, Lopez AD. Global mortality, disability, and the contribution of risk factors: global burden of disease study. Lancet. 1997;349:1436–1442. doi: 10.1016/S0140-6736(96)07495-8. - DOI - PubMed
    1. Knapp M, Mangalore R, Simon J. The global costs of schizophrenia. Schizophr Bull. 2004;30(2):279–293. doi: 10.1093/oxfordjournals.schbul.a007078. - DOI - PubMed
    1. Tan H-Y, Choo W-C, Doshi S, Lim LEC, Kua E-H. A community study of the health-related quality of life of schizophrenia and general practice outpatients in Singapore. Artic Soc Psychiatry Psychiatr Epidemiol. 2004;39:106–112. doi: 10.1007/s00127-004-0717-9. - DOI - PubMed
    1. de Souza LA, Coutinho ESF. The quality of life of people with schizophrenia living in community in Rio de Janeiro, Brazil. Soc Psychiatry Psychiatr Epidemiol. 2006:1–10. 10.1007/s00127-006-0042-6. - PubMed
    1. Evans S, Banerjee S, Leese M, Huxley P. The impact of mental illness on quality of life: a comparison of severe mental illness, common mental disorder and healthy population samples. Qual Life Res. 2007;16(1):17–29. doi: 10.1007/s11136-006-9002-6. - DOI - PubMed

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