Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Observational Study
. 2021 Jan 28;47(1):18.
doi: 10.1186/s13052-021-00977-x.

Transition of inflammatory bowel disease patients from pediatric to adult care: an observational study on a joint-visits approach

Antonio Corsello #  1 , Daniela Pugliese #  2 , Fiammetta Bracci  3 , Daniela Knafelz  3 , Bronislava Papadatou  3 , Marina Aloi  4 , Salvatore Cucchiara  4 , Luisa Guidi  2 , Antonio Gasbarrini  2   5 , Alessandro Armuzzi  2   5
Affiliations
Observational Study

Transition of inflammatory bowel disease patients from pediatric to adult care: an observational study on a joint-visits approach

Antonio Corsello et al. Ital J Pediatr. .

Abstract

Background: Transition from pediatric to adult care of patients affected by Inflammatory Bowel Disease (IBD) is a critical step that needs specific care and multidisciplinary involvement. The aim of our study was to evaluate the outcome of the transition process of a cohort of IBD patients, exploring their readiness and the possible impact on quality of life.

Methods: This observational study followed transitioned IBD patients from pediatric to adult care. Transition was carried-out through combined visits, jointly performed by the pediatrician and the adult gastroenterologist. Clinical data were collected before and after transition. A subgroup of patients was submitted to an anonymous online questionnaire of 38 items based on the validated questionnaires TRAQ and SIBDQ within the first 6 months from the beginning of the transition process.

Results: Eighty-two patients with IBD were enrolled, with a mean age at transition of 20.2±2.7 years. Before transition, 40.2% of patients already had major surgery and 64.6% started biologics. At transition, 24% of patients were in moderate to severe active phase of their disease and 40% of them had already been treated with ≥ 2 biologics. The mean score of the TRAQ questionnaires collected is 3.4±1.5 and the mean score of SIBDQ is 53.9±9.8. A significant association was found between a TRAQ mean score > 3 and a SIBDQ > 50 (p=0.0129). Overall, 75% of patients had a positive opinion of the transition model adopted.

Conclusions: A strong association has been found between TRAQ and SIBDQ questionnaires, showing how transition readiness has a direct impact on the quality of life of the young adult with IBD.

Keywords: Crohn’s disease; Pediatric IBD; SIBDQ; TRAQ; Transition; Ulcerative colitis.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Association between probability of undergoing surgery before transition and clinical activity at diagnosis (HBI and PMS)
Fig. 2
Fig. 2
Transitioned patients divided by age and clinical disease activity
Fig. 3
Fig. 3
Association between TRAQ and SIBDQ scores
Fig. 4
Fig. 4
Association between SIBDQ and TRAQ scores
See this image and copyright information in PMC

References

    1. Kappelman MD, Moore KR, Allen JK, Cook SF. Recent Trends in the prevalence of crohn’s disease and ulcerative colitis in a commercially insured us population. Dig Dis Sci. 2013;58:519–525. Available from: https://doi.org/10.1007/s10620-012-2371-5 - PMC - PubMed
    1. Chaparro M, Garre A, Ricart E, Iglesias-Flores E, Taxonera C, Domènech E, et al. Differences between childhood- and adulthood-onset inflammatory bowel disease: the CAROUSEL study from GETECCU. Aliment Pharmacol Ther. 2019;49:419–428. Available from: https://doi.org/10.1111/apt.15114 - PubMed
    1. Mackner LM, Greenley RN, Szigethy E, Herzer M, Deer K, Hommel KA. Psychosocial issues in pediatric inflammatory bowel disease: report of the North American society for pediatric gastroenterology, hepatology, and nutrition. J Pediatr Gastroenterol Nutr. 2013;56(4):449–58. 10.1097/MPG.0b013e3182841263. Available from: https://journals.lww.com/jpgn/Fulltext/2013/04000/Psychosocial_Issues_in.... - PMC - PubMed
    1. Stollon N, Zhong Y, Ferris M, Bhansali S, Pitts B, Rak E, et al. Chronological age when healthcare transition skills are mastered in adolescents/young adults with inflammatory bowel disease. World J Gastroenterol. 2017;23:3349–3355. doi: 10.3748/wjg.v23.i18.3349. - DOI - PMC - PubMed
    1. Philpott JR, Kurowski JA. Challenges in transitional care in inflammatory bowel disease: a review of the current literature in transition readiness and outcomes. Inflamm Bowel Dis. 2018;25:45–55. Available from: https://doi.org/10.1093/ibd/izy207 - PubMed

Publication types