Transcontinental Dissemination of the L2b/D-Da Recombinant Chlamydia trachomatis Lymphogranuloma venereum (LGV) Strain: Need of Broad Multi-Country Molecular Surveillance

Vítor Borges¹, Joana Isidro¹, Cristina Correia¹, Dora Cordeiro¹, Luís Vieira¹, Zohra Lodhia¹, Cândida Fernandes², Ana Maria Rodrigues², Jacinta Azevedo³, João Alves³, João Roxo⁴, Miguel Rocha⁴, Rita Côrte-Real², Cristina Toscano⁵, Maria Ana Pessanha⁵, Israel Nissan⁶, Shlomo Pilo⁶, Efrat Rorman⁶, Zeev Dveyrin⁶, Yossi Paitan^{7

8}, Haim Paran⁹, Gal Wagner-Kolasko¹⁰, Jennifer Beirnes¹¹, Suzanne Gibbons¹¹, Alberto Severini^{11

12}, Maria José Borrego¹, João Paulo Gomes¹

Affiliations

¹ National Institute of Health Dr. Ricardo Jorge, Lisbon, Portugal.
² Centro Hospitalar e Universitário de Lisboa Central, Lisbon, Portugal.
³ Lapa Health Centre, Lisbon, Portugal.
⁴ CheckpointLX, Grupo de Ativistas em Tratamentos, Lisbon, Portugal.
⁵ Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal.
⁶ National Public Health Laboratories, Tel Aviv, Israel.
⁷ Department of Clinical Microbiology and Immunology, Sackler Faculty of Medicine & Tel Aviv University, Tel Aviv, Israel.
⁸ Clinical Microbiology Lab, Meir Medical Center, Kfar Saba, Israel.
⁹ Department of General Surgery A, Meir Medical Center, Kfar Saba, Israel.
¹⁰ Department of Family Medicine, Clalit Gan-Meir LGBT Clinic, Tel Aviv, Israel.
¹¹ Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
¹² Department of Medical Microbiology, Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.

PMID: 33512482
DOI: 10.1093/cid/ciab067

Transcontinental Dissemination of the L2b/D-Da Recombinant Chlamydia trachomatis Lymphogranuloma venereum (LGV) Strain: Need of Broad Multi-Country Molecular Surveillance

Vítor Borges et al. Clin Infect Dis. 2021.

. 2021 Aug 16;73(4):e1004-e1007.

doi: 10.1093/cid/ciab067.

Authors

Affiliations

¹ National Institute of Health Dr. Ricardo Jorge, Lisbon, Portugal.
² Centro Hospitalar e Universitário de Lisboa Central, Lisbon, Portugal.
³ Lapa Health Centre, Lisbon, Portugal.
⁴ CheckpointLX, Grupo de Ativistas em Tratamentos, Lisbon, Portugal.
⁵ Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal.
⁶ National Public Health Laboratories, Tel Aviv, Israel.
⁷ Department of Clinical Microbiology and Immunology, Sackler Faculty of Medicine & Tel Aviv University, Tel Aviv, Israel.
⁸ Clinical Microbiology Lab, Meir Medical Center, Kfar Saba, Israel.
⁹ Department of General Surgery A, Meir Medical Center, Kfar Saba, Israel.
¹⁰ Department of Family Medicine, Clalit Gan-Meir LGBT Clinic, Tel Aviv, Israel.
¹¹ Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
¹² Department of Medical Microbiology, Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.

PMID: 33512482
DOI: 10.1093/cid/ciab067

Abstract

Previously, we identified a Chlamydia trachomatis lymphogranuloma venereum (LGV) recombinant strain possessing a non-LGV ompA genotype. Here, culture-independent genome sequencing confirms its circulation in Europe, Middle East, and North America, and unveils emergence of antibiotic resistance. Broad surveillance is needed.

Keywords: Chlamydia trachomatis; fluoroquinolones resistance; intercontinental dissemination; lymphogranuloma venereum (LGV); recombination.

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Toward the Spread of the New L2b/D-Da Hybrid Chlamydia trachomatis Strain in Men Who Have Sex With Men in France?
Carrer M, de Barbeyrac B, Laurier-Nadalié C, Bébéar C, Touati A, Peuchant O. Carrer M, et al. Clin Infect Dis. 2021 Sep 15;73(6):1130-1131. doi: 10.1093/cid/ciab253. Clin Infect Dis. 2021. PMID: 33744938 No abstract available.

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Transcontinental Dissemination of the L2b/D-Da Recombinant Chlamydia trachomatis Lymphogranuloma venereum (LGV) Strain: Need of Broad Multi-Country Molecular Surveillance

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Transcontinental Dissemination of the L2b/D-Da Recombinant Chlamydia trachomatis Lymphogranuloma venereum (LGV) Strain: Need of Broad Multi-Country Molecular Surveillance

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