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Review
. 2021 Jan;43(1):54-60.
doi: 10.1055/s-0040-1721856. Epub 2021 Jan 29.

COVID-19: Uncertainties from Conception to Birth

Bruno Ramalho de Carvalho  1 , Karina de Sá Adami  2 , Walusa Assad Gonçalves-Ferri  3 , Marise Samama  4 , Rui Alberto Ferriani  5 , Alessandra Cristina Marcolin  5
Affiliations
Review

COVID-19: Uncertainties from Conception to Birth

Bruno Ramalho de Carvalho et al. Rev Bras Ginecol Obstet. 2021 Jan.

Abstract
in English, Portuguese

Scientific information on the impact of the new coronavirus (SARS-CoV-2) on the health of pregnant women, fetuses and newborns is considered of limited confidence, lacking good-quality evidence, and drawing biased conclusions. As a matter of fact, the initial impressions that the evolution of COVID-19 was no different between pregnant and non-pregnant women, and that SARS-CoV-2 was not vertically transmitted, are confronted by the documentation of worsening of the disease during pregnancy, poor obstetric outcomes, and the possibility of vertical transmission. The present article aims to compile the data available on the association of COVID-19 and reproductive events, from conception to birth.

As informações científicas sobre o impacto do novo coronavírus, SARS-CoV-2, na saúde de gestantes, fetos e recém-nascidos são consideradas de confiabilidade limitada, sem evidências de boa qualidade, e levam a conclusões enviesadas. De fato, as impressões iniciais de que a evolução da Covid-19 não era diferente entre mulheres grávidas e não grávidas, e de que o SARS-CoV-2 não era transmitido verticalmente, são confrontadas pela documentação de agravamentos da doença durante a gravidez, resultados obstétricos negativos, e a possibilidade de transmissão vertical. Este artigo tem como objetivo compilar os dados disponíveis sobre a associação entre a Covid-19 e os eventos reprodutivos, desde a concepção até o nascimento.

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Conflict of interest statement

The authors have no conflict of interests to declare.

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