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. 2021 Jan 27;10(2):262.
doi: 10.3390/foods10020262.

Quality of Dabai Pulp Oil Extracted by Supercritical Carbon Dioxide and Supplementation in Hypercholesterolemic Rat-A New Alternative Fat

Noor Atiqah Aizan Abdul Kadir  1 , Azrina Azlan  1   2   3 , Faridah Abas  4 , Intan Safinar Ismail  5
Affiliations

Quality of Dabai Pulp Oil Extracted by Supercritical Carbon Dioxide and Supplementation in Hypercholesterolemic Rat-A New Alternative Fat

Noor Atiqah Aizan Abdul Kadir et al. Foods. .

Abstract

Dabai pulp oil (DPO) is new oil extracted from the pulp of Canarium odontophyllum. The quality and efficacy of DPO are needed to promote its potential as a new alternative fat. Therefore, we investigate the quality of DPO, which includes moisture and volatile content (MVC), free fatty acid content (FFA), iodine value (IV), and peroxide value (PV). Furthermore, we evaluate the efficacy of DPO against hypercholesterolemia elicited by a high-cholesterol diet in rats. The MVC of DPO was <0.001 ± 0.00%. Next, the FFA in DPO was 2.57 ± 0.03%, and the IV of DPO was 53.74 ± 0.08 g iodine/100 g oil. Meanwhile, the PV of DPO was 4.97 ± 0.00 mEq/kg. Supplementation of DPO in hypercholesterolemic rats for 30 days revealed the hypocholesterolemic effect (significant reduction of total cholesterol, triglyceride, and 3-hydroxy-3-methylglutaryl-CoA reductase) accompanied by a significant reduction of inflammatory markers (C-reactive protein, interleukin-6 and tumour necrosis factor-α), and lipid peroxidation (MDA). We also observed a significant improvement of lipoprotein lipase (LPL) and antioxidant capacities (total antioxidant status, superoxide dismutase, glutathione peroxidase, and catalase) of the rats. The results on the quality and efficacy of locally made DPO suggest its potential use as a healthy alternative fat in the future.

Keywords: alternative fat; anti-inflammatory; antioxidant; dabai pulp oil; hypercholesterolemia.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Schematic diagram of the supercritical carbon dioxide extraction system.
See this image and copyright information in PMC

References

    1. Jelani N.A.A., Azlan A., Ismail A., Khoo H.E., Alinafia S.M. Fatty acid profiles and antioxidant properties of dabai oil. ScienceAsia. 2017;43:347–353. doi: 10.2306/scienceasia1513-1874.2017.43.347. - DOI
    1. SAzlan A., Prasad K.N., Khoo H.E., Abdul-Aziz N., Mohamad A., Ismail A., Amom Z. Comparison of fatty acids, vitamin E and physicochemical properties of Canarium odontophyllum Miq. (dabai), olive and palm oils. J. Food Compos. Anal. 2010;23:772–776. doi: 10.1016/j.jfca.2010.03.026. - DOI
    1. Shakirin F.H., Azlan A., Ismail A., Amom Z., Yuon L.C. Antiatherosclerotic effect of canarium odontophyllum Miq. Fruit parts in rabbits fed high cholesterol diet. Evid.-Based Complement. Altern. Med. 2012;2012:838604. doi: 10.1155/2012/838604. - DOI - PMC - PubMed
    1. Shakirin F.H., Azlan A., Ismail A., Amom Z., Lau C.Y. Protective effect of pulp oil extracted from canarium odontophyllum Miq. fruit on blood lipids, lipid peroxidation, and antioxidant status in healthy rabbits. Oxid. Med. Cell. Longev. 2012;2012:840973. doi: 10.1155/2012/840973. - DOI - PMC - PubMed
    1. Martínez J.L. Supercritical Fluid Extraction of Nutraceuticals and Bioactive Compounds. Taylor & Francis Group; Boca Raton, FL, USA: 2007.

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