A comparative trial of co-trimoxazole and amoxycillin in the treatment of acute exacerbations of chronic bronchitis

Abstract

A single-blind comparative trial of the effectiveness of co-trimoxazole and amoxycillin in the treatment of acute exacerbations of chronic bronchitis was carried out on 60 hospital patients. Both forms of treatment were equally effective in producing clinical improvement and reduction of sputum purulence and volume. There was no significant difference, either in the speed of recovery, or in the relapse rate, after treatment with co-trimoxazole and amoxycillin.