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Editorial
. 2021 Feb 1;106(2):326-328.
doi: 10.3324/haematol.2020.266627.

Ironing out an approach to alleviate the hypoferremia of acute inflammation

Affiliations
Editorial

Ironing out an approach to alleviate the hypoferremia of acute inflammation

Karin E Finberg. Haematologica. .
No abstract available

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Figures

Figure 1.
Figure 1.
Physiological responses to lipopolysaccharide (LPS), an inducer of acute inflammation, are modulated in mice by pretreatment with the C-terminal portion of the endocrine hormone FGF23 (C-FGF23). The attenuated responses involve parameters that are relevant to systemic iron balance and the development of the anemia of inflammation.

Comment on

References

    1. Weiss G, Ganz T, Goodnough LT. Anemia of inflammation. Blood. 2019;133(1):40-50. - PMC - PubMed
    1. Agoro R, Park MY, Le Henaff C, et al. C-FGF23 peptide alleviates hypoferremia during acute inflammation. Haematologica. 2020;106(2):391-403. - PMC - PubMed
    1. Drakesmith H, Nemeth E, Ganz T. Ironing out ferroportin. Cell Metab. 2015;22(5):777-787. - PMC - PubMed
    1. Camaschella C, Nai A, Silvestri L. Iron metabolism and iron disorders revisited in the hepcidin era. Haematologica. 2020;105(2):260-272. - PMC - PubMed
    1. Peyssonnaux C, Zinkernagel AS, Datta V, Lauth X, Johnson RS, Nizet V. TLR4-dependent hepcidin expression by myeloid cells in response to bacterial pathogens. Blood. 2006;107(9):3727-3732. - PMC - PubMed