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Meta-Analysis
. 2021 Dec;47(3):690-702.
doi: 10.1111/aej.12487. Epub 2021 Feb 1.

Solubility of bioceramic- and epoxy resin-based root canal sealers: A systematic review and meta-analysis

Emmanuel J N L Silva  1 , Milla Lessa Cardoso  2 , Jéssica Perrut Rodrigues  2 , Gustavo De-Deus  2 , Tatiana Kelly da Silva Fidalgo  3
Affiliations
Meta-Analysis

Solubility of bioceramic- and epoxy resin-based root canal sealers: A systematic review and meta-analysis

Emmanuel J N L Silva et al. Aust Endod J. 2021 Dec.

Abstract

This systematic review and meta-analysis evaluated whether epoxy resin-based root canal sealers present an increased solubility than calcium silicate-based root canal sealers. A systematic search was performed in the following databases: PubMed, Science Direct, Scopus, Web of Science and Open Grey. The inclusion criteria consisted of in vitro studies that compared the solubility of epoxy resin-based and calcium silicate-based sealers. The quality assessment and data extraction of the selected articles were performed. The meta-analysis of the pooled data and the subgroups according to the root thirds were carried out using the RevMan software (P < 0.05). After the duplicate removal and eligibility criteria assessment, a total of 22 studies were included all of them were considered as having a low risk of bias. The meta-analysis demonstrated overall lower solubility of AH Plus. AH Plus presented lower solubility than Bio-C Sealer, BioRoot RCS, MTA Fillapex, Sealer Plus and Total Fill BC Sealer.

Keywords: calcium silicate; mineral trioxide aggregate; root canal sealers; solubility; systematic review.

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