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Comment
. 2021 Feb;39(2):158-159.
doi: 10.1038/s41587-020-00810-6. Epub 2021 Feb 1.

UMI or not UMI, that is the question for scRNA-seq zero-inflation

Yingying Cao  1 , Simo Kitanovski  1 , Ralf Küppers  2 , Daniel Hoffmann  3
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Comment

UMI or not UMI, that is the question for scRNA-seq zero-inflation

Yingying Cao et al. Nat Biotechnol. 2021 Feb.
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References

    1. Svensson, V. Droplet scRNA-seq is not zero-inflated Nat. Biotechnol. 38, 147–150 (2020).
    1. Kivioja, T. et al. Counting absolute numbers of molecules using unique molecular identifiers. Nat. Methods 9, 72–74 (2012). - DOI
    1. Islam, S. et al. Quantitative single-cell RNA-seq with unique molecular identifiers. Nat. Methods 11, 163–166 (2014). - DOI
    1. Ding, J. et al. Systematic comparison of single-cell and single-nucleus RNA-sequencing methods. Nat. Biotechnol. 38, 737–746 (2020). - DOI
    1. Chen, W. et al. UMI-count modeling and differential expression analysis for single-cell RNA sequencing. Genome Biol. 19, 70 (2018). - DOI

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