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Review
. 2021 Jan 1;18(5):1121-1129.
doi: 10.7150/ijms.51594. eCollection 2021.

Environmental Pollution and Chronic Kidney Disease

Hui-Ju Tsai  1   2   3   4 , Pei-Yu Wu  5   6 , Jiun-Chi Huang  5   6   7 , Szu-Chia Chen  4   5   6   7
Affiliations
Review

Environmental Pollution and Chronic Kidney Disease

Hui-Ju Tsai et al. Int J Med Sci. .

Abstract

Chronic kidney disease (CKD) is a global public health problem associated with high rates of morbidity and mortality due to end-stage renal disease and cardiovascular disease. Safe and effective medications to reverse or stabilize renal function in patients with CKD are lacking, and hence it is important to identify modifiable risk factors associated with worsening kidney function. Environmental pollutants, including metals, air pollutant, phthalate and melamine can potentially increase the risk of CKD or accelerate its progression. In this review, we discuss the epidemiological evidence for the association between environmental pollution and kidney disease, including heavy metals, air pollution and other environmental nephrotoxicants in the general population.

Keywords: chronic kidney disease; environmental pollution; heavy metal.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interest exists.

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