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. 2021;30(1):1-25.
doi: 10.1007/s40629-020-00158-y. Epub 2021 Jan 28.

Guideline (S2k) on acute therapy and management of anaphylaxis: 2021 update: S2k-Guideline of the German Society for Allergology and Clinical Immunology (DGAKI), the Medical Association of German Allergologists (AeDA), the Society of Pediatric Allergology and Environmental Medicine (GPA), the German Academy of Allergology and Environmental Medicine (DAAU), the German Professional Association of Pediatricians (BVKJ), the Society for Neonatology and Pediatric Intensive Care (GNPI), the German Society of Dermatology (DDG), the Austrian Society for Allergology and Immunology (ÖGAI), the Swiss Society for Allergy and Immunology (SGAI), the German Society of Anaesthesiology and Intensive Care Medicine (DGAI), the German Society of Pharmacology (DGP), the German Respiratory Society (DGP), the patient organization German Allergy and Asthma Association (DAAB), the German Working Group of Anaphylaxis Training and Education (AGATE)

Affiliations

Guideline (S2k) on acute therapy and management of anaphylaxis: 2021 update: S2k-Guideline of the German Society for Allergology and Clinical Immunology (DGAKI), the Medical Association of German Allergologists (AeDA), the Society of Pediatric Allergology and Environmental Medicine (GPA), the German Academy of Allergology and Environmental Medicine (DAAU), the German Professional Association of Pediatricians (BVKJ), the Society for Neonatology and Pediatric Intensive Care (GNPI), the German Society of Dermatology (DDG), the Austrian Society for Allergology and Immunology (ÖGAI), the Swiss Society for Allergy and Immunology (SGAI), the German Society of Anaesthesiology and Intensive Care Medicine (DGAI), the German Society of Pharmacology (DGP), the German Respiratory Society (DGP), the patient organization German Allergy and Asthma Association (DAAB), the German Working Group of Anaphylaxis Training and Education (AGATE)

Johannes Ring et al. Allergo J Int. 2021.
No abstract available

Keywords: Adrenalin; Anaphylaxis; Auto-injector; COVID-19; Drug allergy; Emergency management; Food allergy; Group education; Pharmacotherapy; Vaccination.

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Conflict of interest statement

Conflict of interestConflict of interest statements—in addition to the guideline report—can be found in tabular form and accessed on the AWMF website for the S2k guideline on “acute therapy and management of anaphylaxis: 2020 update” (www.awmf.org/leitlinien/detail/ll/061-025.html).

Figures

Fig. 1
Fig. 1
Risk factors for anaphylactic reactions
Fig. 2
Fig. 2
Algorithm for prehospital airway management (from [58]). EGA epiglottic airway, ETI endotracheal intubation
Fig. 3
Fig. 3
Acute treatment of the most common anaphylactic patterns. Inh inhaled
Fig. 4
Fig. 4
Anaphylaxis emergency plan

References

    1. Johansson SG, Bieber T, Dahl R, Friedmann PS, Lanier BQ, Lockey RF, et al. Revised nomenclature for allergy for global use: Report of the Nomenclature Review Committee of the World Allergy Organization. J Allergy Clin Immunol. 2004;113:832–836. doi: 10.1016/j.jaci.2003.12.591. - DOI - PubMed
    1. Ring J, editor. Anaphylaxis. Basel: Karger; 2010.
    1. Simons FE, Ardusso LR, Bilò MB, El-Gamal YM, Ledford DK, Ring J, et al. World Allergy Organization anaphylaxis guidelines: summary. J Allergy Clin Immunol. 2011;127:587–93.e1–22. doi: 10.1016/j.jaci.2011.01.038. - DOI - PubMed
    1. Tryba M, Ahnefeld FW, Barth J, Dick W, Doenicke A, Fuchs T, et al. Akuttherapie anaphylaktoider Reaktionen. Ergebnisse einer interdisziplinären Konsensuskonferenz. Allergo J. 1994;3:211–224. - PubMed
    1. Ring J, Brockow K, Duda D, Eschenhagen T, Fuchs T, Huttegger I, et al. Akuttherapie anaphylaktischer Reaktionen. Leitlinie der Deutschen Gesellschaft für Allergologie und klinische Immunologie (DGAKI), des Ärzteverbandes Deutscher Allergologen (ÄDA), der Gesellschaft für Pädiatrische Allergologie und Umweltmedizin (GPA) und der Deutschen Akademie für Allergologie und Umweltmedizin (DAAU) Allergo J. 2007;16:420–434. doi: 10.1007/BF03370705. - DOI