Clinical Trial
[Cimetidine in the treatment of peptic ulcer]
[Article in
Italian]
- PMID: 335279
Item in Clipboard
Clinical Trial
[Cimetidine in the treatment of peptic ulcer]
[Article in
Italian]
Minerva Med.
.
Abstract
Cimetidine, a non-thiourea-containing histamine H2-receptor antagonist, has been employed in the treatment of peptic ulcer. We studied 50 patients, partly with double-blind method, and partly in a free trial. Duodenal ulcers were completely healed in 80% of the cases, at the control endoscopy after a 4-week period of treatment with cimetidine (1000 mg/day). Peptic ulcer in general healed in 76% of the cases. Gastric secretion was significantly reduced after cimetidine. An important improvement in subjective symptoms was noted in every patient. No toxic effect was noted.
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