Procalcitonin for the differential diagnosis of COVID-19 in the emergency department. Prospective monocentric study

doi:10.1007/s11739-021-02641-y

. 2021 Sep;16(6):1733-1735.

doi: 10.1007/s11739-021-02641-y. Epub 2021 Feb 2.

Procalcitonin for the differential diagnosis of COVID-19 in the emergency department. Prospective monocentric study

Peiman Nazerian¹, Manfredi Gagliano², Lorenzo Roberto Suardi³, Alessandra Fanelli⁴, Gian Maria Rossolini⁵, Stefano Grifoni²; “ED COVID-19” Investigators

Collaborators, Affiliations

Collaborators

“ED COVID-19” Investigators:
Antonio Annovi, Alessio Prota, Enrico Lumini, Elisabetta Catini, Simona Gualtieri, Barbara Casanova, Eleonora De Villa, Gabriele Cerini, Sara Mucaj, Marco Albanesi, Edoardo Cavigli, Chiara Moroni, Vittorio Miele, Fillippo Lagi, Lucia Turco, Matteo Tomaiuolo, Diana Paolini, Barbara Tognetti

Affiliations

¹ Department of Emergency Medicine, Careggi University Hospital, largo Brambilla 3, 50134, Firenze, Italy. pnazerian@hotmail.com.
² Department of Emergency Medicine, Careggi University Hospital, largo Brambilla 3, 50134, Firenze, Italy.
³ Department of Infectious Diseases, Santa Maria Annunziata Hospital, Bagno a Ripoli, Firenze, Italy.
⁴ Department of General Laboratory, Careggi University Hospital, Firenze, Italy.
⁵ Department of Experimental and Clinical Medicine, University of Florence and Microbiology and Virology Unit, Careggi University Hospital, Firenze, Italy.

PMID: 33528740
PMCID: PMC7851503
DOI: 10.1007/s11739-021-02641-y

Procalcitonin for the differential diagnosis of COVID-19 in the emergency department. Prospective monocentric study

Peiman Nazerian et al. Intern Emerg Med. 2021 Sep.

. 2021 Sep;16(6):1733-1735.

doi: 10.1007/s11739-021-02641-y. Epub 2021 Feb 2.

Authors

Peiman Nazerian¹, Manfredi Gagliano², Lorenzo Roberto Suardi³, Alessandra Fanelli⁴, Gian Maria Rossolini⁵, Stefano Grifoni²; “ED COVID-19” Investigators

Collaborators

“ED COVID-19” Investigators:
Antonio Annovi, Alessio Prota, Enrico Lumini, Elisabetta Catini, Simona Gualtieri, Barbara Casanova, Eleonora De Villa, Gabriele Cerini, Sara Mucaj, Marco Albanesi, Edoardo Cavigli, Chiara Moroni, Vittorio Miele, Fillippo Lagi, Lucia Turco, Matteo Tomaiuolo, Diana Paolini, Barbara Tognetti

Affiliations

¹ Department of Emergency Medicine, Careggi University Hospital, largo Brambilla 3, 50134, Firenze, Italy. pnazerian@hotmail.com.
² Department of Emergency Medicine, Careggi University Hospital, largo Brambilla 3, 50134, Firenze, Italy.
³ Department of Infectious Diseases, Santa Maria Annunziata Hospital, Bagno a Ripoli, Firenze, Italy.
⁴ Department of General Laboratory, Careggi University Hospital, Firenze, Italy.
⁵ Department of Experimental and Clinical Medicine, University of Florence and Microbiology and Virology Unit, Careggi University Hospital, Firenze, Italy.

PMID: 33528740
PMCID: PMC7851503
DOI: 10.1007/s11739-021-02641-y

No abstract available

PubMed Disclaimer

Conflict of interest statement

None of the authors and of the study investigators report conflict of interest except for Prof. Rossolini that received honoraria by Thermofisher for participation in advisory boards on PCT diagnostic use in bacterial infections.

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References

1. West CP, Montori VM, Sampathkumar P. COVID-19 testing: the threat of false- negative results. Mayo clinic Proc. 2020;95:1127–1129. doi: 10.1016/j.mayocp.2020.04.004. - DOI - PMC - PubMed
1. Kamat IS, Ramachandran V, Eswaran H, Guffey D, Musher DM. Procalcitonin to distinguish viral from bacterial pneumonia: a systematic review and meta-analysis. Clin Infect Dis. 2020;70(3):538–542. doi: 10.1093/cid/ciz545. - DOI - PubMed
1. Hoeboer SH, van der Geest PJ, Nieboer D, Groeneveld AB. The diagnostic accuracy of procalcitonin for bacteraemia: a systematic review and meta-analysis. Clin Microbiol Infect. 2015;21(5):474–481. doi: 10.1016/j.cmi.2014.12.026. - DOI - PubMed
1. So-Ngern A, Leelasupasri S, Chulavatnatol S, Pummangura C, Bunupuradah P, Montakantikul P. Prognostic value of serum procalcitonin level for the diagnosis of bacterial infections in critically-ill patients. Infect Chemother. 2019;51(3):263–273. doi: 10.3947/ic.2019.51.3.263. - DOI - PMC - PubMed

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[1] West CP, Montori VM, Sampathkumar P. COVID-19 testing: the threat of false- negative results. Mayo clinic Proc. 2020;95:1127–1129. doi: 10.1016/j.mayocp.2020.04.004. - DOI - PMC - PubMed

[2] West CP, Montori VM, Sampathkumar P. COVID-19 testing: the threat of false- negative results. Mayo clinic Proc. 2020;95:1127–1129. doi: 10.1016/j.mayocp.2020.04.004. - DOI - PMC - PubMed

[3] Kamat IS, Ramachandran V, Eswaran H, Guffey D, Musher DM. Procalcitonin to distinguish viral from bacterial pneumonia: a systematic review and meta-analysis. Clin Infect Dis. 2020;70(3):538–542. doi: 10.1093/cid/ciz545. - DOI - PubMed

[4] Kamat IS, Ramachandran V, Eswaran H, Guffey D, Musher DM. Procalcitonin to distinguish viral from bacterial pneumonia: a systematic review and meta-analysis. Clin Infect Dis. 2020;70(3):538–542. doi: 10.1093/cid/ciz545. - DOI - PubMed

[5] Hoeboer SH, van der Geest PJ, Nieboer D, Groeneveld AB. The diagnostic accuracy of procalcitonin for bacteraemia: a systematic review and meta-analysis. Clin Microbiol Infect. 2015;21(5):474–481. doi: 10.1016/j.cmi.2014.12.026. - DOI - PubMed

[6] Hoeboer SH, van der Geest PJ, Nieboer D, Groeneveld AB. The diagnostic accuracy of procalcitonin for bacteraemia: a systematic review and meta-analysis. Clin Microbiol Infect. 2015;21(5):474–481. doi: 10.1016/j.cmi.2014.12.026. - DOI - PubMed

[7] So-Ngern A, Leelasupasri S, Chulavatnatol S, Pummangura C, Bunupuradah P, Montakantikul P. Prognostic value of serum procalcitonin level for the diagnosis of bacterial infections in critically-ill patients. Infect Chemother. 2019;51(3):263–273. doi: 10.3947/ic.2019.51.3.263. - DOI - PMC - PubMed

[8] So-Ngern A, Leelasupasri S, Chulavatnatol S, Pummangura C, Bunupuradah P, Montakantikul P. Prognostic value of serum procalcitonin level for the diagnosis of bacterial infections in critically-ill patients. Infect Chemother. 2019;51(3):263–273. doi: 10.3947/ic.2019.51.3.263. - DOI - PMC - PubMed

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Procalcitonin for the differential diagnosis of COVID-19 in the emergency department. Prospective monocentric study

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Procalcitonin for the differential diagnosis of COVID-19 in the emergency department. Prospective monocentric study

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