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. 2016 May:(81):NTP-TOX-81.
doi: 10.22427/NTP-TOX-81.

Toxicity studies of α-pinene administered by inhalation to F344/N rats and B6C3F1/N mice

National Toxicology Program  1
Collaborators, Affiliations

Toxicity studies of α-pinene administered by inhalation to F344/N rats and B6C3F1/N mice

National Toxicology Program. Toxic Rep Ser. 2016 May.

Abstract

α-Pinene is the main component in turpentine and is used as a fragrance and flavoring ingredient. Due to widespread exposure potential and a lack of available toxicity data, male and female F344/N rats and B6C3F1/N mice were exposed to α-pinene (96% pure) by inhalation for 2 weeks or 3 months. Genetic toxicology studies were conducted in Salmonella typhimurium, Escherichia coli, and mouse peripheral blood erythrocytes. (Abstract Abridged).

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