Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Sep-Oct;12(5):197-204.
doi: 10.4103/ijt.ijt_99_20. Epub 2020 Nov 3.

Cumulative Life Course Impairment of Alopecia Areata

Affiliations
Review

Cumulative Life Course Impairment of Alopecia Areata

Laura J Burns et al. Int J Trichology. 2020 Sep-Oct.

Abstract

Alopecia areata (AA), an unpredictable, nonscarring hair loss, is commonly perceived as a cosmetic, rather than medical, concern. However, substantial evidence exists describing the negative impact on quality of life, as the disease affects patients personally, socially, financially, and physically. Over time, the cumulative disability may perpetuate poor confidence, social disconnection, negative coping strategies, and failure to achieve a full life potential. Here, we describe the cumulative life course impairment (CLCI) of AA by examining the complex interaction of (1) stigmatization, (2) physical and psychiatric comorbidities, and (3) coping strategies. The model aggregates existing cross-sectional data, which have previously captured disease burden only as snapshots in time. Thus, by examining cumulative effects, the CLCI model serves as a proxy for longitudinal data to better describe life course epidemiology of the disease.

Keywords: Alopecia areata; cumulative life course impairment; quality of life.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

References

    1. Safavi K. Prevalence of alopecia areata in theFirst National Health and Nutrition Examination Survey. Arch Dermatol. 1992;128:702. - PubMed
    1. Mirzoyev SA, Schrum AG, Davis MD, Torgerson RR. Lifetime incidence risk of alopecia areata estimated at 2.1% by Rochester Epidemiology Project, 1990-2009. J Invest Dermatol. 2014;134:1141–2. - PMC - PubMed
    1. Safavi KH, Muller SA, Suman VJ, Moshell AN, Melton LJ., 3rd Incidence of alopecia areata in Olmsted County, Minnesota, 1975 through 1989. Mayo Clin Proc. 1995;70:628–33. - PubMed
    1. Kyriakis KP, Paltatzidou K, Kosma E, Sofouri E, Tadros A, Rachioti E. Alopecia areata prevalence by gender and age. J Eur Acad Dermatol Venereol. 2009;23:572–3. - PubMed
    1. Lyakhovitsky A, Aronovich A, Gilboa S, Baum S, Barzilai A. Alopecia areata: A long-term follow-up study of 104 patients. J Eur Acad Dermatol Venereol. 2019;33:1602–9. - PubMed