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. 2021 Jan 23;6(1):e12063.
doi: 10.1002/trc2.12063. eCollection 2020.

Advancing family dementia caregiver interventions in low- and middle-income countries: A pilot cluster randomized controlled trial of Resources for Advancing Alzheimer's Caregiver Health in Vietnam (REACH VN)

Ladson Hinton  1 , Huong Nguyen  2 , Hung Trong Nguyen  3   4 , Danielle J Harvey  5 , Linda Nichols  6   7 , Jennifer Martindale-Adams  6   7 , Binh Thanh Nguyen  3 , Binh Thi Thanh Nguyen  3 , Anh Ngoc Nguyen  3 , Chinh Hong Nguyen  3 , Thu Thi Hoai Nguyen  3 , Thuy Le Nguyen  3 , Anh Thi Phuong Nguyen  3 , Ngoc Bich Nguyen  3 , Quyen Q Tiet  8 , Tuan Anh Nguyen  9 , Phong Quy Nguyen  3 , Trung Anh Nguyen  3   4 , Thang Pham  3   4
Affiliations

Advancing family dementia caregiver interventions in low- and middle-income countries: A pilot cluster randomized controlled trial of Resources for Advancing Alzheimer's Caregiver Health in Vietnam (REACH VN)

Ladson Hinton et al. Alzheimers Dement (N Y). .

Abstract

Introduction: Low- and middle-income countries have rapidly increasing numbers of people with dementia, yet little evidence on family caregiving interventions. We tested the preliminary efficacy and feasibility of a family caregiving intervention in northern Vietnam.

Methods: Nine clusters comprising 60 family caregivers were randomized to a culturally adapted version of a four- to six-session, multicomponent intervention delivered in-home over 2 to 3 months, or enhanced control. Eligible caregivers were ≥18 years of age and scored ≥6 on the Zarit Burden Inventory (ZBI).

Results: Fifty-one caregivers (85%) completed the study. Using analysis of covariance with 3-month assessment as the outcome and baseline assessment as a covariate, intervention group caregivers had an average ZBI (primary outcome) score 1.2 standard deviation (SD) lower (P = .02) and Patient Health Questionnaire-4 (psychological distress) score 0.7 SD lower (P = .03) than controls.

Discussion: In the first study of its kind in Vietnam, a culturally adapted, manualized, family caregiver intervention was both efficacious and feasible.

Keywords: Alzheimer's disease; Vietnam; dementia; family caregiving; global health; low ‐and middle‐income countries; non‐pharmacological interventions.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

FIGURE 1
FIGURE 1
Effect size for primary and secondary caregiver outcomes in a cluster randomized controlled trial (RCT)
FIGURE 2
FIGURE 2
Consort diagram or recruitment for pilot cluster randomized controlled trial (RCT)
See this image and copyright information in PMC

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