Further Evidence that Habitual Consumption of Sucralose with, but Not without, Carbohydrate Alters Glucose Metabolism

Jelle R Dalenberg¹, Raphael Denis², Serge Luquet³, Dana M Small⁴

Affiliations

¹ Department of Neuroendocrinology, Groningen Institute for Evolutionary Life Sciences, University of Groningen, Groningen, the Netherlands.
² Université de Paris, BFA, UMR 8251, CNRS, 75014 Paris, France.
³ Université de Paris, BFA, UMR 8251, CNRS, 75014 Paris, France; Modern Diet and Physiology Research Center (MDPRC), New Haven, CT, USA.
⁴ Modern Diet and Physiology Research Center (MDPRC), New Haven, CT, USA; Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA; Department of Psychology, Yale University, New Haven, CT 06510, USA. Electronic address: dana.small@yale.edu.

PMID: 33535095
DOI: 10.1016/j.cmet.2021.01.006

Free article

Comment

Further Evidence that Habitual Consumption of Sucralose with, but Not without, Carbohydrate Alters Glucose Metabolism

Jelle R Dalenberg et al. Cell Metab. 2021.

Free article

. 2021 Feb 2;33(2):227-228.

doi: 10.1016/j.cmet.2021.01.006.

Authors

Jelle R Dalenberg¹, Raphael Denis², Serge Luquet³, Dana M Small⁴

Affiliations

¹ Department of Neuroendocrinology, Groningen Institute for Evolutionary Life Sciences, University of Groningen, Groningen, the Netherlands.
² Université de Paris, BFA, UMR 8251, CNRS, 75014 Paris, France.
³ Université de Paris, BFA, UMR 8251, CNRS, 75014 Paris, France; Modern Diet and Physiology Research Center (MDPRC), New Haven, CT, USA.
⁴ Modern Diet and Physiology Research Center (MDPRC), New Haven, CT, USA; Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA; Department of Psychology, Yale University, New Haven, CT 06510, USA. Electronic address: dana.small@yale.edu.

PMID: 33535095
DOI: 10.1016/j.cmet.2021.01.006

Abstract

In this letter, Dalenberg et al. provide a point-by-point response to the critique offered by Kahn and Sievenpiper. They also offer new evidence to support their original finding from a study they conducted in mice.

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Comment on

Short-Term Consumption of Sucralose with, but Not without, Carbohydrate Impairs Neural and Metabolic Sensitivity to Sugar in Humans.
Dalenberg JR, Patel BP, Denis R, Veldhuizen MG, Nakamura Y, Vinke PC, Luquet S, Small DM. Dalenberg JR, et al. Cell Metab. 2020 Mar 3;31(3):493-502.e7. doi: 10.1016/j.cmet.2020.01.014. Cell Metab. 2020. PMID: 32130881 Free PMC article. Clinical Trial.
Low-Calorie Sweeteners with Carbohydrate Do Not Impair Insulin Sensitivity in Humans: Re-analysis Highlighting the Importance of the Comparator.
Khan TA, Sievenpiper JL. Khan TA, et al. Cell Metab. 2021 Feb 2;33(2):225-226. doi: 10.1016/j.cmet.2020.10.024. Cell Metab. 2021. PMID: 33535094

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Further Evidence that Habitual Consumption of Sucralose with, but Not without, Carbohydrate Alters Glucose Metabolism

Affiliations

Further Evidence that Habitual Consumption of Sucralose with, but Not without, Carbohydrate Alters Glucose Metabolism

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Abstract

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