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Case Reports
. 2021 Feb 1;8(1):29-32.
doi: 10.3390/dermatopathology8010005.

Primary Dermal Melanoma: A Rare Clinicopathological Variant Mimicking Metastatic Melanoma

Oriana Simonetti  1 , Elisa Molinelli  1 , Valerio Brisigotti  1 , Donatella Brancorsini  2 , Davide Talevi  3 , Annamaria Offidani  1
Affiliations
Case Reports

Primary Dermal Melanoma: A Rare Clinicopathological Variant Mimicking Metastatic Melanoma

Oriana Simonetti et al. Dermatopathology (Basel). .

Abstract

Primary dermal melanoma (PDM) is a rare distinct variant of cutaneous melanoma, predominantly occurring on the extremities of young or middle-aged adults. In comparison to conventional melanoma, PDM is characterized by unexpectedly prolonged survival and long-term survival. Thus, correct identification of this variant is crucial to avoid potential misdiagnosis and establish correct treatment and follow-up. In addition, no consensus and specific guidelines exist on the management of this peculiar subtype of cutaneous melanoma.

Keywords: cutaneous melanoma; cutaneous metastatic melanoma; dermal melanoma; histopathologic diagnosis; primary dermal melanoma; prognosis.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
(a) Pink nodule with a peripheral erythematous halo of the chest. (b) Dermoscopic pattern of nodular lesion: reddish-purplish homogeneous pattern, with atypical vessels.
Figure 2
Figure 2
(a) Well-circumscribed dermal nodule with no involvement of the epidermis (EE × 2) (b) Proliferation of atypical and pleomorphic melanocytes with mitotic activity (EE × 200).
See this image and copyright information in PMC

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