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. 2021 Feb 1;9(2):144.
doi: 10.3390/healthcare9020144.

Effects of Topical Hydrogen Purification on Skin Parameters and Acne Vulgaris in Adult Women

Karolina Chilicka  1 , Aleksandra M Rogowska  2 , Renata Szyguła  1
Affiliations

Effects of Topical Hydrogen Purification on Skin Parameters and Acne Vulgaris in Adult Women

Karolina Chilicka et al. Healthcare (Basel). .

Abstract

Background: Acne vulgaris is a prevalent dermatological disease characterized by skin eruptions, which may decrease the sufferer's quality of life. Hydrogen purification treatment is a new procedure used in cosmetology to improve the skin parameters of the face. This study examined the effectiveness of hydrogen purification treatment to improve women's skin conditions with regard to acne vulgaris.

Methods: In this study, 30 women participated who suffered from a high level of sebum and acne. The control group was comprised of 30 healthy women with a low level of sebum. The Hellgren-Vincent Scale and Derma Unit SSC 3 device were used to assess acne vulgaris severity and skin properties, respectively. Four hydrogen purification sessions were carried out at 7-day intervals, using the Hebe Hydrogenium+ generating alkaline water.

Results: At baseline and 7 and 14 days after finishing the series of treatments, the levels of oiliness, moisture, and skin pH were tested. The main effects of treatment were significant in the following parameters: pH around the bottom lip, moisture between the eyebrows and around the nose, and oily skin in all three face sites.

Conclusions: The level of sebum decreased and moisture levels increased during hydrogen purification. Topical hydrogen purification is an effective and safe treatment for acne vulgaris.

Keywords: acne vulgaris; alkaline water; hydrogen purification.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Consort flow chart of clinical study group 1 (acne vulgaris, AV) and group 2 (control sample, CS).
Figure 2
Figure 2
Hebe Hydrogenium+.
Figure 3
Figure 3
Example of participant’s forehead: (A) from AV group before hydrogen purification (HP); (B) from CS group before HP; (C) from AV group 14 days after HP; (D) from CS group after HP.
Figure 4
Figure 4
Differences in the HVS between two measurements: at baseline and 14 days after finishing the 4-week treatment of hydrogen purification.
Figure 5
Figure 5
Comparison of mean values of skin acidity at baseline, one week, and two weeks after finishing the treatment with hydrogen purification in both AV and CS groups. Error bars are standard deviations.
Figure 6
Figure 6
Comparison of mean values of oily skin at baseline, one week, and two weeks after finishing the treatment with hydrogen purification in both AV and CS groups. Error bars are standard deviations.
Figure 7
Figure 7
Comparison of mean values of moisture skin at baseline, one week, and two weeks after finishing the treatment with hydrogen purification in both AV and CS groups. Error bars are standard deviations.
See this image and copyright information in PMC

References

    1. Heng A.W.S., Chew F.T. Systematic review of the epidemiology of acne vulgaris. Sci. Rep. 2020;10:5754. doi: 10.1038/s41598-020-62715-3. - DOI - PMC - PubMed
    1. Dréno B. Treatment of adult female acne: A new challenge. J. Eur. Acad. Dermatol. Venereol. 2015;29:14–19. doi: 10.1111/jdv.13188. - DOI - PubMed
    1. Anaba E.L., Oaku R.I. Adult female acne: A cross-sectional study of diet, family history, body mass index, and premenstrual flare as risk factors and contributors to severity. Int. J. Women Dermatol. 2020 doi: 10.1016/j.ijwd.2020.11.008. - DOI - PMC - PubMed
    1. Picardi A., Lega I., Tarolla E. Suicide risk in skin disorders. Clin. Dermatol. 2013;31:47–56. doi: 10.1016/j.clindermatol.2011.11.006. - DOI - PubMed
    1. Jagtiani A., Nishal P., Jangid P., Sethi S., Dayal S., Kapoor A. Depression and suicidal ideation in patients with acne, psoriasis, and alopecia areata. J. Mental Health Hum. Behav. 2017;22:50–54. doi: 10.4103/0971-8990.210700. - DOI