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. 2021 Feb 3;19(1):50.
doi: 10.1186/s12967-021-02721-9.

Off label use of Aripiprazole shows promise as a treatment for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): a retrospective study of 101 patients treated with a low dose of Aripiprazole

L D Crosby  1 , S Kalanidhi  1 , A Bonilla  1   2 , A Subramanian  1 , J S Ballon  1 , H Bonilla  3
Affiliations

Off label use of Aripiprazole shows promise as a treatment for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): a retrospective study of 101 patients treated with a low dose of Aripiprazole

L D Crosby et al. J Transl Med. .

Erratum in

No abstract available

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Conflict of interest statement

The authors of this manuscript do not have a conflict of interest, or competing interests.

Figures

Fig. 1
Fig. 1
Changes in symptom severity scores between Responders and Non-Responders taking aripiprazole. Symptoms were rated on a scale of 0 (no symptom) to 10 (worst). For responders, average fatigue score changed by − 2.89 units (p < 0.001), brain fog changed by − 2.33 units (p < 0.001), and unrefreshing sleep changed by − 2.05 units (p < 0.001). Non-Responders showed non-significant differences of − 0.2 units for fatigue, (p = 1), − 0.65 units for brain fog (p = 0.289), and = 0.42 for unrefreshing sleep (p = 0.4105)
See this image and copyright information in PMC

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