A new route to regulating AMPK activity

Comment

Sarah Crunkhorn. Nat Rev Drug Discov. 2021 Mar.

. 2021 Mar;20(3):175.

doi: 10.1038/d41573-021-00021-x.

No abstract available

Comment on

A Fbxo48 inhibitor prevents pAMPKα degradation and ameliorates insulin resistance.
Liu Y, Jurczak MJ, Lear TB, Lin B, Larsen MB, Kennerdell JR, Chen Y, Huckestein BR, Nguyen MK, Tuncer F, Jiang Y, Monga SP, O'Donnell CP, Finkel T, Chen BB, Mallampalli RK. Liu Y, et al. Nat Chem Biol. 2021 Mar;17(3):298-306. doi: 10.1038/s41589-020-00723-0. Epub 2021 Jan 25. Nat Chem Biol. 2021. PMID: 33495648 Free PMC article.

1. Liu, Y. et al. A Fbxo48 inhibitor prevents pAMPKα degradation and ameliorates insulin resistance. Nat. Chem. Bio. https://doi.org/10.1038/s41589-020-00723-0 (2021)