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Review
. 2021 Jan 16;14(1):100500.
doi: 10.1016/j.waojou.2020.100500. eCollection 2021 Jan.

Perspectives on decisions for treatment and care in severe asthma

Tonya Winders  1 , Jorge Maspero  2 , Luke Callan  3 , Mona Al-Ahmad  4
Affiliations
Review

Perspectives on decisions for treatment and care in severe asthma

Tonya Winders et al. World Allergy Organ J. .

Abstract

Background: Severe asthma is a subtype of asthma that can be hard to control, resulting in an exceptional impact on an individual's quality of life. The aim of this review article is to explore the misalignment of perceptions of severe asthma among different stakeholders to identify how to reduce burden and improve delivery of care.

Results: The misalignment of perspectives is best reflected in randomised controlled trials (RCTs) in asthma treatments, which are often designed for regulatory approval with a focus on exacerbations with no direct input from the individuals that the treatments are designed for. Based on a literature review and the clinical experience of the authors to overcome this disparity, the goals of people with severe asthma need to be incorporated throughout their care, from study design to the day-to-day management of their condition. Improved education for individuals and their support network will provide them with resources and knowledge so that they can effectively communicate their needs to other stakeholders involved in their care.

Conclusion/recommendation: A collaborative effort from all stakeholders is essential to ensure efficient management of asthma and a reduction in asthma burden on individuals and society.

Keywords: Burden; Perspective; Severe asthma.

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Conflict of interest statement

MA-A and TW declare that they have no competing interests. LC is an employee of ASTRAZENECA and owns shares. JM reports grants, personal fees and non-financial support from ASTRAZENECA and SANOFI; grants from NOVARTIS; personal fees and non-financial support from INMUNOTEK; personal fees from URIACH; grants and non-financial support from GSK, outside the submitted work.

Figures

Fig. 1
Fig. 1
Results from a patient organisation survey conducted across 17 countries.
Fig. 2
Fig. 2
Perspectives on treatment and care from people with severe asthma: current unmet needs and solutions. PCP: primary care physician; RCT: randomised controlled trial.
See this image and copyright information in PMC

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