Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Jan;57(1):68-75.
doi: 10.4068/cmj.2021.57.1.68. Epub 2021 Jan 25.

Association between Alcohol Drinking Status and Depressive Symptoms in Korean Adults

Affiliations

Association between Alcohol Drinking Status and Depressive Symptoms in Korean Adults

Jung-Hwa Yang et al. Chonnam Med J. 2021 Jan.

Abstract

We investigated the association between alcohol drinking status and depressive symptoms in a representative sample of South Korean adults using data from the 2017 Korea Community Health Survey (KCHS), which included 216,771 participants (99,845 men and 116,926 women). Depression was defined as a Patient Health Questionnaire-9 score of ≥10. Multivariate logistic regression using sampling weights was used to assess the relationship between alcohol drinking status and depression after adjusting for potential confounders. Alcohol intake was nonlinearly associated with depression; the risk of depression was the lowest in men who were moderate drinkers and women who were light drinkers. In men, heavy drinkers (odds ratio [OR] 1.41, 95% confidence interval [CI] 1.19-1.67), light drinkers (OR 1.13, 95% CI 0.94-1.36), infrequent drinkers (OR 1.31, 95% CI 1.00-1.73), and lifetime abstainers (OR 1.38, 95% CI 1.09-1.75) were at a higher risk of depression than moderate drinkers. In women, moderate drinkers (OR 1.19, 95% CI 1.02-1.40) and heavy drinkers (OR 1.56, 95% CI 1.33-1.84) were at a higher risk of depression than light drinkers; however, infrequent drinkers and lifetime abstainers were not at a high risk of depression. In both men and women, former drinkers were at a higher risk of depression (OR 1.61, 95% CI 1.34-1.93 and OR 1.25, 95% CI 1.09-1.43, respectively). In conclusion, the association between alcohol drinking status and depression was nonlinear in both sexes. Further investigation of age- and sex-specific factors related to the association between alcohol use and depression is needed.

Keywords: Alcohol Drinking; Depression; Health Surveys; Patient Health Questionnaire 9.

PubMed Disclaimer

Conflict of interest statement

CONFLICT OF INTEREST STATEMENT: None declared.

Figures

FIG. 1
FIG. 1. Age-stratified analysis for estimated prevalence of depressive symptoms according to sex. All models were adjusted for age, marital status, education, household income, residential area, body mass index, smoking status, hypertension, diabetes, arthritis, and self-rated health.

References

    1. GBD 2016 Alcohol Collaborators. Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2018;392:1015–1035. - PMC - PubMed
    1. Shin HY, Kim J, Lee S, Park MS, Park S, Huh S. Cause-of-death statistics in 2018 in the Republic of Korea. J Korean Med Assoc. 2020;63:286–297.
    1. Blanco C, Alegría AA, Liu SM, Secades-Villa R, Sugaya L, Davies C, et al. Differences among major depressive disorder with and without co-occurring substance use disorders and substance-induced depressive disorder: results from the National Epidemiologic Survey on Alcohol and Related Conditions. J Clin Psychiatry. 2012;73:865–873. - PubMed
    1. Flensborg-Madsen T, Mortensen EL, Knop J, Becker U, Sher L, Grønbaek M. Comorbidity and temporal ordering of alcohol use disorders and other psychiatric disorders: results from a Danish register-based study. Compr Psychiatry. 2009;50:307–314. - PubMed
    1. Li J, Wang H, Li M, Shen Q, Li X, Zhang Y, et al. Effect of alcohol use disorders and alcohol intake on the risk of subsequent depressive symptoms: a systematic review and meta-analysis of cohort studies. Addiction. 2020;115:1224–1243. - PubMed