A chemotherapy-free regimen for Philadelphia chromosome-positive acute lymphoblastic leukemia: are we there yet?
- PMID: 33538156
- PMCID: PMC8252952
- DOI: 10.3324/haematol.2020.278077
A chemotherapy-free regimen for Philadelphia chromosome-positive acute lymphoblastic leukemia: are we there yet?
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A multicenter total therapy strategy for de novo adult Philadelphia chromosome positive acute lymphoblastic leukemia patients: final results of the GIMEMA LAL1509 protocol.Haematologica. 2021 Jul 1;106(7):1828-1838. doi: 10.3324/haematol.2020.260935. Haematologica. 2021. PMID: 33538150 Free PMC article.
References
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- Vignetti M, Fazi P, Cimino G, et al. . Imatinib plus steroids induces complete remissions and prolonged survival in elderly Philadelphia chromosome-positive patients with acute lymphoblastic leukemia without additional chemotherapy: results of the Gruppo Italiano Malattie Ematologiche dell'Adulto (GIMEMA) LAL0201-B protocol. Blood. 2007;109(9):3676-3678. - PubMed
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- Foa R, Vitale A, Vignetti M, et al. . Dasatinib as first-line treatment for adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia. Blood. 2011;118(25):6521-6528. - PubMed
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- FDA Guidance Document: Hematologic Malignancies: Regulatory Considerations for use of minimal residual disease in development of drug and biological products for treatment. Available at https://www.fda.gov/media/134605/download. Accessed in December, 2020.
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