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. 2021 Feb 3;109(3):401-403.
doi: 10.1016/j.neuron.2020.12.024.

The Ups and Downs of Firing Rate Homeostasis

R Irene Jacobsen  1 , Tara Keck  2
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Free article
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The Ups and Downs of Firing Rate Homeostasis

R Irene Jacobsen et al. Neuron. .
Free article

Abstract

Torrado Pacheco et al. demonstrate that downward firing rate homeostasis occurs when cellular activity levels increase beyond baseline, but only during sleep-dense periods. In contrast, Hebbian-facilitated changes in firing rate occur independently of sleep and wake states.

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  • Sleep Promotes Downward Firing Rate Homeostasis.
    Torrado Pacheco A, Bottorff J, Gao Y, Turrigiano GG. Torrado Pacheco A, et al. Neuron. 2021 Feb 3;109(3):530-544.e6. doi: 10.1016/j.neuron.2020.11.001. Epub 2020 Nov 23. Neuron. 2021. PMID: 33232655 Free PMC article.

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