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. 2020 Apr-Jun;61(2):583-585.
doi: 10.47162/RJME.61.2.31.

The bursa of Hieronymus Fabricius ab Aquapendente: from original iconography to most recent research

Domenico Ribatti  1 , Andrea Porzionato, Aron Emmi, Raffaele De Caro
Affiliations

The bursa of Hieronymus Fabricius ab Aquapendente: from original iconography to most recent research

Domenico Ribatti et al. Rom J Morphol Embryol. 2020 Apr-Jun.

Abstract

Hieronymus Fabricius ab Aquapendente (1533-1619) described the homonymous bursa in the "De Formatione Ovi et Pulli", published posthumously in 1621. He also included a figure in which the bursa was depicted. We here present the figure of the bursa of Fabricius, along with corrections of some mislabeling still presents in some anastatic copies. The bursa of Fabricius is universally known as the origin of B-lymphocytes; morphogenetical and physiological issues are also considered.

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Conflict of interest statement

The authors declare that they have no conflict of interests.

Figures

Figure 1
Figure 1
(A) Original description of the bursa of Fabricius in the “De Formatione Ovi et Pulli”. (B and C) Original figure of the above-mentioned manuscript showing the bursa of Fabricius. (D) Original figure legend.
Figure 2
Figure 2
(A and B) Anastatic copy of the figure of the “De Formatione Ovi et Pulli” manuscript with incorrect labeling. (C) Original figure legend.
See this image and copyright information in PMC

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References

    1. Smith SB, Macchi V, Parenti A, De Caro R. Hieronymus Fabricius Ab Acquapendente (1533-1619) Clin Anat. Erratum in: Clin Anat. 2004;2005;1718(7)(2):540–543. 154–154. - PubMed
    1. Porzionato A, Macchi V, Stecco C, Parenti A, De Caro R. The anatomical school of Padua. Anat Rec (Hoboken) 2012;295(6):902–916. - PubMed
    1. Zanchin G, De Caro R. The nervous system in colours: the tabulae pictae of G.F. d’Acquapendente (ca. 1533–1619) J Headache Pain. 2006;7(5):360–366. - PMC - PubMed
    1. Adelman HB. The embryological treaties of Hieronymus Fabricius of Acquapendente. Ithaca, New York: Cornell University Press; 1967. pp. 147–191.
    1. Hamilton HL. Lillie’s development of the chick – and introduction to embryology. 3. New York: Henry Holt & Co; Rinehart and Winston; 1952. pp. 390–391.